Concentration of Credit Risk (Details)	3 Months Ended		9 Months Ended		12 Months Ended
	Sep. 30, 2017	Sep. 30, 2016	Sep. 30, 2017	Sep. 30, 2016	Dec. 31, 2016
Contract Revenues | Customer Concentration Risk | Collaboration Partner A
Concentration of risk
Percentage of concentration risk			24.00%	7.00%
Contract Revenues | Customer Concentration Risk | Collaboration Partner B
Concentration of risk
Percentage of concentration risk	100.00%	100.00%	76.00%	93.00%
Sales Revenue | Customer Concentration Risk | Customer A
Concentration of risk
Percentage of concentration risk	24.00%	25.00%	25.00%	26.00%
Sales Revenue | Customer Concentration Risk | Customer B
Concentration of risk
Percentage of concentration risk	16.00%	19.00%	16.00%	18.00%
Sales Revenue | Customer Concentration Risk | Customer C
Concentration of risk
Percentage of concentration risk	14.00%	13.00%	13.00%	13.00%
Sales Revenue | Customer Concentration Risk | Customer D
Concentration of risk
Percentage of concentration risk	8.00%	8.00%	8.00%	8.00%
Accounts Receivable | Credit Concentration Risk | Collaboration Partner A and B
Concentration of risk
Percentage of concentration risk			23.00%		23.00%
Accounts Receivable | Credit Concentration Risk | Customer A B C and D
Concentration of risk
Percentage of concentration risk			44.00%		41.00%