CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands		Sep. 30, 2017	Dec. 31, 2016
Current assets:
Cash and cash equivalents		$ 1,128,046	$ 652,343	[1]
Marketable securities-available-for-sale		153,343	156,203	[1]
Accounts receivable		198,345	148,758	[1]
Inventory		3,261	4,106	[1]
Prepaid expenses and other current assets		58,327	32,768	[1]
Total current assets		1,541,322	994,178	[1]
Restricted cash and investments		926	886	[1]
Long term investment		169,020	31,987	[1]
Inventory		11,297	15,193	[1]
Property and equipment, net		246,825	167,679	[1]
Other intangible assets, net		242,285	258,437	[1]
In-process research and development	[1]		12,000
Goodwill		155,593	155,593	[1]
Other assets, net		7,033	2,644	[1]
Total assets		2,374,301	1,638,597	[1]
Current liabilities:
Accounts payable		69,933	75,599	[1]
Accrued compensation		61,274	50,904	[1]
Interest payable		100	762	[1]
Accrued and other current liabilities		164,298	126,697	[1]
Acquisition-related contingent consideration		24,330	19,539	[1]
Total current liabilities		319,935	273,501	[1]
Convertible senior notes		23,711	651,481	[1]
Acquisition-related contingent consideration		259,670	281,461	[1]
Other liabilities		13,235	12,687	[1]
Total liabilities		616,551	1,219,130	[1]
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000,000 shares authorized; none issued or outstanding as of September 30, 2017 and December 31, 2016				[1]
Common stock, $0.001 par value; 400,000,000 shares authorized; 211,019,366 and 188,848,752 shares issued and outstanding as of September 30, 2017 and December 31, 2016, respectively		211	189	[1]
Additional paid-in capital		3,585,403	2,096,929	[1]
Accumulated other comprehensive income (loss)		12,512	(2,886)	[1]
Accumulated deficit		(1,840,376)	(1,674,765)	[1]
Total stockholders' equity		1,757,750	419,467	[1]
Total liabilities and stockholders' equity		$ 2,374,301	$ 1,638,597	[1]

[1] The condensed consolidated balance sheet at December 31, 2016 has been derived from the audited financial statements at that date.