CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Jun. 30, 2017	Dec. 31, 2016	[1]
Current assets:
Cash and cash equivalents	$ 451,754	$ 652,343
Marketable securities-available-for-sale	156,852	156,203
Accounts receivable	169,516	148,758
Inventory	2,930	4,106
Prepaid expenses and other current assets	63,751	32,768
Total current assets	844,803	994,178
Restricted cash and investments	943	886
Long term investment	144,425	31,987
Inventory	11,907	15,193
Property and equipment, net	218,878	167,679
Other intangible assets, net	247,669	258,437
In-process research and development	12,000	12,000
Goodwill	155,593	155,593
Other assets, net	3,225	2,644
Total assets	1,639,443	1,638,597
Current liabilities:
Accounts payable	69,093	75,599
Accrued compensation	50,902	50,904
Interest payable	34	762
Accrued and other current liabilities	150,353	126,697
Acquisition-related contingent consideration	22,779	19,539
Total current liabilities	293,161	273,501
Convertible senior notes	23,428	651,481
Acquisition-related contingent consideration	283,221	281,461
Other liabilities	12,798	12,687
Total liabilities	612,608	1,219,130
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000,000 shares authorized; none issued or outstanding as of June 30, 2017 and December 31, 2016
Common stock, $0.001 par value; 400,000,000 shares authorized; 205,630,980 and 188,848,752 shares issued and outstanding as of June 30, 2017 and December 31, 2016, respectively	205	189
Additional paid-in capital	2,892,092	2,096,929
Accumulated other comprehensive income (loss)	10,968	(2,886)
Accumulated deficit	(1,876,430)	(1,674,765)
Total stockholders' equity	1,026,835	419,467
Total liabilities and stockholders' equity	$ 1,639,443	$ 1,638,597

[1] The condensed consolidated balance sheet at December 31, 2016 has been derived from the audited financial statements at that date.