Concentration of Credit Risk (Details)	3 Months Ended		12 Months Ended
	Mar. 31, 2017	Mar. 31, 2016	Dec. 31, 2016
Contract Revenues | Customer Concentration Risk | Collaboration Partner A
Concentration of risk
Percentage of concentration risk	28.00%
Contract Revenues | Customer Concentration Risk | Collaboration Partner B
Concentration of risk
Percentage of concentration risk	72.00%	100.00%
Sales Revenue | Customer Concentration Risk | Customer A
Concentration of risk
Percentage of concentration risk	27.00%	27.00%
Sales Revenue | Customer Concentration Risk | Customer B
Concentration of risk
Percentage of concentration risk	16.00%	18.00%
Sales Revenue | Customer Concentration Risk | Customer C
Concentration of risk
Percentage of concentration risk	13.00%	12.00%
Sales Revenue | Customer Concentration Risk | Customer D
Concentration of risk
Percentage of concentration risk	8.00%	8.00%
Accounts Receivable | Credit Concentration Risk | Collaboration Partner A and B
Concentration of risk
Percentage of concentration risk	49.00%		23.00%
Accounts Receivable | Credit Concentration Risk | Customer A B C and D
Concentration of risk
Percentage of concentration risk	27.00%		41.00%