CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Mar. 31, 2017	Dec. 31, 2016	[1]
Current assets:
Cash and cash equivalents	$ 361,823	$ 652,343
Marketable securities-available-for-sale	150,132	156,203
Accounts receivable	244,975	148,758
Inventory	3,961	4,106
Prepaid expenses and other current assets	58,284	32,768
Total current assets	819,175	994,178
Restricted cash and investments	902	886
Long term investment	158,322	31,987
Inventory	14,548	15,193
Property and equipment, net	193,211	167,679
Other intangible assets, net	253,053	258,437
In-process research and development	12,000	12,000
Goodwill	155,593	155,593
Other assets, net	543	2,644
Total assets	1,607,347	1,638,597
Current liabilities:
Accounts payable	86,327	75,599
Accrued compensation	54,622	50,904
Interest payable	135	762
Accrued and other current liabilities	142,104	126,697
Acquisition-related contingent consideration	21,528	19,539
Total current liabilities	304,716	273,501
Convertible senior notes	41,604	651,481
Acquisition-related contingent consideration	282,472	281,461
Other liabilities	12,621	12,687
Total liabilities	641,413	1,219,130
Stockholders' equity:
Preferred stock, $0.001 par value; 5,000,000 shares authorized; none issued or outstanding as of December 31, 2016 and December 31, 2015
Common stock, $0.001 par value; 400,000,000 shares authorized; 204,563,710 and 188,848,752 shares issued and outstanding as of March 31, 2017 and December 31, 2016, respectively	205	189
Additional paid-in capital	2,824,298	2,096,929
Accumulated other comprehensive income (loss)	5,377	(2,886)
Accumulated deficit	(1,863,946)	(1,674,765)
Total stockholders' equity	965,934	419,467
Total liabilities and stockholders' equity	$ 1,607,347	$ 1,638,597

[1] The condensed consolidated balance sheet at December 31, 2016 has been derived from the audited financial statements at that date.