Concentration of Credit Risk (Details)	3 Months Ended		12 Months Ended
	Mar. 31, 2016	Mar. 31, 2015	Dec. 31, 2015
Contract Revenues | Customer Concentration Risk | Collaboration Partner A
Concentration of risk
Percentage of concentration risk		89.00%
Contract Revenues | Customer Concentration Risk | Collaboration Partner B
Concentration of risk
Percentage of concentration risk	100.00%	11.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer A
Concentration of risk
Percentage of concentration risk	27.00%	28.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer B
Concentration of risk
Percentage of concentration risk	18.00%	20.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer C
Concentration of risk
Percentage of concentration risk	12.00%	13.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer D
Concentration of risk
Percentage of concentration risk	8.00%	8.00%
Accounts Receivable | Credit Concentration Risk | Collaboration Partner A and B
Concentration of risk
Percentage of concentration risk	22.00%		39.00%
Accounts Receivable | Credit Concentration Risk | Customer A B C and D
Concentration of risk
Percentage of concentration risk	48.00%		40.00%