Concentration of Credit Risk (Details)	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Contract Revenues | Customer Concentration Risk | Collaboration Partner A
Concentration of risk
Percentage of concentration risk	83.00%	88.00%	86.00%
Contract Revenues | Customer Concentration Risk | Collaboration Partner B
Concentration of risk
Percentage of concentration risk	17.00%	12.00%	14.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer A
Concentration of risk
Percentage of concentration risk	28.00%	29.00%	29.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer B
Concentration of risk
Percentage of concentration risk	19.00%	22.00%	17.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer C
Concentration of risk
Percentage of concentration risk	13.00%	10.00%	11.00%
Sales Revenue Goods Services Net | Customer Concentration Risk | Customer D
Concentration of risk
Percentage of concentration risk	9.00%	9.00%	11.00%
Accounts Receivable | Credit Concentration Risk | Collaboration Partner A and B
Concentration of risk
Percentage of concentration risk	39.00%	26.00%
Accounts Receivable | Credit Concentration Risk | Customer A B C and D
Concentration of risk
Percentage of concentration risk	40.00%	54.00%