X0508 4 2023-07-14 0 0000879169 INCYTE CORP INCY 0001596492 Hoppenot Herve 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 1 1 0 1 Chairman / CEO President 0 Common Stock 2023-07-14 4 A 0 43184 0.00 A 434856 D Commont Stock 25900 I By GRAT Employee Stock Option (right to buy) 61.76 2023-07-14 4 A 0 90563 0.00 A 2033-07-13 Common Stock 90563 90563 D Represents award of restricted stock units ("RSUs") that will vest 25% annually over four years, subject to Herve Hoppenot's continued service with the Issuer through the applicable vesting dates. The RSUs may be settled only for shares of common stock on a one-for-one basis. Including the July 14, 2023 RSU Grant, this includes an aggregate of 133,685 shares of common stock issuable pursuant to previously reported RSUs and earned performance shares that have not vested. The July 14, 2023 options become exercisable in 37 installments, with the first 25% vesting after one year and the remainder vesting monthly over three years. /s/ Elizabeth Feeney, Attorney-In-Fact 2023-07-18