X0306 4 2022-01-31 0 0000879169 INCYTE CORP INCY 0001780561 Dickinson Jonathan Elliott 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 0 1 0 0 EVP, General Manager, Europe Common Stock 2022-01-31 4 S 0 7375 74.19 D 30214 D Reporting person undertakes to provide upon request by Securities and Exchange Commission, the issuer or a securityholder of the issuer detailed information regarding the price and number of shares sold within range indicated. Represents weighted average sale price. Actual sale prices ranged from $73.61 to $74.57 This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person. Includes an aggregate of 19,705 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. /s/ Elizabeth Feeney, Attorney-In-Fact 2022-02-02