X0306 4 2021-01-15 0 0000879169 INCYTE CORP INCY 0001615842 Flannelly Barry P 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 0 1 0 0 EVP & General Manager US Common Stock 2021-01-15 4 A 0 11522 0.00 A 52738 D Employee Stock Option (right to buy) 90.56 2021-01-15 4 A 0 12743 0.00 A 2031-01-14 Common Stock 12743 12743 D Represents award of restricted stock units ("RSUs") that will vest 100% on the fourth anniversary of the grant date of January 15, 2021, subject to Barry Flannelly's continued service with the issuer through the applicable vesting date. The RSUs may be settled only for shares of common stock on a one-for-one basis. Including the January 17, 2020 Restricted Stock Unit Grant, this includes an aggregate of 44,704 shares of common stock issuable pursuant to previously reported restricted stock units and earned performance stock units that have not vested. Beginning January 15, 2021, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2021 and the remainder vesting monthly over three years. /s/ Barry Flannelly 2021-01-20