X0306 4 2019-04-26 0 0000879169 INCYTE CORP INCY 0001236927 FRIEDMAN PAUL A 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 1 0 0 0 Common Stock 2019-04-26 4 A 0 1520 0.00 A 255531 D Common Stock 15000 I By Grat Employee Stock Option (right to buy) 75.03 2019-04-26 4 A 0 12472 0.00 A 2029-04-25 Common Stock 12472 12472 D This award of restricted stock units ("RSUs") vests in full on the first anniversary of the date of grant or, if earlier, the date of the next regular annual meeting of the Company's stockholders or upon a change of control (as defined in the RSU plan). The RSUs may be settled only for shares of common stock on a one-for-one basis. Shares were previously reported as directly beneficially owned but were contributed to a grantor retained annuity trust (GRAT) on April 3, 2019. This option vests in full on the first anniversary of the date of grant, or if earlier, the date of the next regular annual meeting of the Company's stockholders or upon change of control (as defined in the option plan). /s/ Michael J. Purvis, Attorney-In-Fact 2019-04-29