X0306 4 2019-01-04 0 0000879169 INCYTE CORP INCY 0001236934 SWAIN PAULA J 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 0 1 0 0 EVP, Human Resources Common Stock 2019-01-04 4 M 0 30000 18.32 A 62324 D Common Stock 2019-01-04 4 S 0 30000 70.00 D 32324 D Common Stock 2019-01-07 4 F 0 1200 74.21 D 31124 D Employee Stock Option (right to buy) 72.27 2019-01-04 4 A 0 22772 0.00 A 2029-01-03 Common Stock 22772 22772 D Employee Stock Option (right to buy) 72.27 2019-01-04 4 A 0 31552 0.00 A 2029-01-03 Common Stock 31552 31552 D Non-Qualified Stock Option (right to buy) 18.32 2019-01-04 4 M 0 30000 0.00 D 2020-02-08 Common Stock 30000 21782 D This transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by reporting person. Represents shares withheld automatically by the Issuer to satisfy tax withholding obligations due at settlement of restricted stock units previously reported in Table I as common stock. This includes an aggregate of 5,416 shares of common stock issuable pursuant to previously reported restricted stock units that have not vested. Beginning January 4, 2019, options become exercisable in 37 installments, with the first 25.00% vesting on July 2, 2019 and the remainder vesting monthly over three years. Beginning January 4, 2019, options become exercisable in full on January 4, 2023. Beginning February 9, 2013, options become exercisable in 25 installments, with the first 33.33% vesting after one year and the remainder vesting monthly over two years. /s/ Paula Swain 2019-01-08