X0306 4 2018-06-29 0 0000879169 INCYTE CORP INCY 0001175940 BROOKE PAUL A 1801 AUGUSTINE CUT-OFF WILMINGTON DE 19803 1 0 0 0 Common Stock 2018-06-20 5 G 0 E 20000 0.00 D 197859 D Common Stock 2018-06-20 5 G 0 E 20000 0.00 A 40000 I By the Paul Brooke Family Trusts Common Stock 2018-06-29 4 A 0 354 67.00 A 198213 D Common Stock 40000 I By the Paul Brooke Family Trusts On June 20, 2018, the reporting person transferred 20,000 directly owned shares of Common Stock to a family trust, The Kathleen McCarrigher and Paul A. Brooke 2012 Family Trust (the "Trust No. 2") for the benefit of the reporting person's descendants. The reporting person's spouse is the trustee of the Trust. The reporting person disclaims beneficial ownership of the shares of Common Stock held by Trust No. 2. As previously reported, the reporting person transferred certain directly owned shares of Common Stock to another family trust, the Paul Brooke Family Trust (the "Trust No. 1"). Collectively, Trust No. 1 and Trust No. 2 are referred to herein and will be referred to in future reports as "The Paul Brooke Family Trusts". Restricted shares issued to the Reporting Person under the Issuer's Amended and Restated 2010 Stock Incentive Plan in lieu of quarterly director retainer fees pursuant to an election by the Reporting Person intended to comply with Rule 10b5-1. Restricted shares are fully vested. /s/ Michael J. Purvis, Attorney-In-Fact 2018-07-03