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Debt (Details) (USD $)
9 Months Ended 5 Months Ended 1 Months Ended
Sep. 30, 2013
Dec. 31, 2012
Sep. 30, 2013
Carrying Amount
Dec. 31, 2012
Carrying Amount
Sep. 30, 2013
Fair Value
Dec. 31, 2012
Fair Value
Dec. 31, 2012
Pfizer convertible subordinated note due 2014
Carrying Amount
Dec. 31, 2012
Pfizer convertible subordinated note due 2014
Fair Value
Sep. 30, 2013
4.75% convertible senior notes due 2015
Dec. 31, 2012
4.75% convertible senior notes due 2015
Sep. 30, 2013
4.75% convertible senior notes due 2015
Carrying Amount
Dec. 31, 2012
4.75% convertible senior notes due 2015
Carrying Amount
Sep. 30, 2013
4.75% convertible senior notes due 2015
Fair Value
Dec. 31, 2012
4.75% convertible senior notes due 2015
Fair Value
Aug. 31, 2013
Pfizer convertible subordinated note due 2013
Convertible Notes                              
Interest rate of debt (as a percent)                 4.75% 4.75%          
Convertible subordinated notes   $ 9,033,000         $ 9,033,000 $ 13,573,000              
Convertible senior notes 187,136,000 322,043,000                 187,136,000 322,043,000 955,974,000 798,040,000  
Long-term debt, noncurrent     187,136,000 331,076,000 955,974,000 811,613,000                  
Aggregate principal amount of notes that can be converted into common stock                 180,988,000           10,000,000
Common stock issued in conversion of notes (in shares)                 20,625,403           1,025,641
Cash used to fund redemption of notes $ 11,262,000               $ 11,300,000