Concentration of Credit Risk (Details)	3 Months Ended		6 Months Ended		3 Months Ended		6 Months Ended		3 Months Ended		6 Months Ended		3 Months Ended		6 Months Ended		3 Months Ended		6 Months Ended		3 Months Ended		6 Months Ended			12 Months Ended	6 Months Ended	12 Months Ended
	Jun. 30, 2013 Total Contract Revenues Customer Concentration Collaboration Partner A	Jun. 30, 2012 Total Contract Revenues Customer Concentration Collaboration Partner A	Jun. 30, 2013 Total Contract Revenues Customer Concentration Collaboration Partner A	Jun. 30, 2012 Total Contract Revenues Customer Concentration Collaboration Partner A	Jun. 30, 2013 Total Contract Revenues Customer Concentration Collaboration Partner B	Jun. 30, 2012 Total Contract Revenues Customer Concentration Collaboration Partner B	Jun. 30, 2013 Total Contract Revenues Customer Concentration Collaboration Partner B	Jun. 30, 2012 Total Contract Revenues Customer Concentration Collaboration Partner B	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer A	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer A	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer A	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer A	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer B	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer B	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer B	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer B	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer C	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer C	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer C	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer C	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer D	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer D	Jun. 30, 2013 Total Net Product Revenues Customer Concentration Customer D	Jun. 30, 2012 Total Net Product Revenues Customer Concentration Customer D	Jun. 30, 2013 Accounts receivable Credit Concentration Collaboration Partner A and Collaboration Partner B	Dec. 31, 2012 Accounts receivable Credit Concentration Collaboration Partner A and Collaboration Partner B	Jun. 30, 2013 Accounts receivable Credit Concentration Customer A, B, C and D	Dec. 31, 2012 Accounts receivable Credit Concentration Customer A, B, C and D
Concentration of risk
Percentage of concentration risk	92.00%	94.00%	89.00%	91.00%	8.00%	6.00%	11.00%	9.00%	29.00%	27.00%	28.00%	30.00%	19.00%	22.00%	19.00%	23.00%	12.00%	15.00%	12.00%	15.00%	11.00%	15.00%	11.00%	14.00%	25.00%	73.00%	55.00%	17.00%