Accrued and Other Current Liabilities (Tables)

12 Months Ended

Dec. 31, 2022

Payables and Accruals [Abstract]

Schedule of accrued and other current liabilities

Accrued and other current liabilities consisted of the following (in thousands):

	December 31,
	2022		2021
Royalties	$	263,466	$	168,412
Clinical related costs	130,570		109,486
Sales allowances	192,133		136,541
Sales and marketing	31,149		35,750
Construction in progress	3,493		27,098
Operating lease liabilities	8,195		10,554
Other current liabilities	72,047		45,754
Total accrued and other current liabilities	$	701,053	$	533,595