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Commitments, Contingencies and Other Matters (Details) (USD $)
3 Months Ended 9 Months Ended 0 Months Ended
Sep. 30, 2014
Dec. 31, 2013
Sep. 30, 2014
Patent Infringement Claim Brought by the Curators of the University of Missouri [Member]
Sep. 30, 2014
Patent Infringement Claim Brought by the Curators of the University of Missouri [Member]
Jun. 30, 2014
Patent Infringement Claim Brought by the Curators of the University of Missouri [Member]
Dec. 31, 2013
Patent Infringement Claim Brought by the Curators of the University of Missouri [Member]
Jul. 17, 2013
TWi Pharmaceuticals [Member]
claim
Jan. 23, 2014
Eli Lilly [Member]
claim
Jan. 24, 2014
Eli Lilly, Daiichi Sankyo, and Ube Industries [Member]
claim
Commitments Contingencies and Other Matters [Line Items]                  
Litigation settlement amount     $ 91,000,000 $ 100,000,000          
Accrued legal settlements $ 0 $ 41,367,000     $ 9,000,000 $ 9,000,000      
Claims dismissed             2    
Loss Contingency, New Claims Filed, Number               2 2