X0202 4 2004-05-06 0000877902 NEOSE TECHNOLOGIES INC NTEC 0001194368 RACHESKY MARK H MD 40 WEST 57TH STREET 24TH FLOOR NEW YORK NY 10019 1 0 0 0 Non-qualified Stock Option (right to buy) 3.0367 2004-05-06 4 A 0 2305 A 2004-05-06 2014-05-06 Common Stock 2305 2305 D Non-qualified Stock Option (right to buy) 9.11 2004-05-06 4 A 0 10000 A 2004-05-06 2014-05-06 Common Stock 10000 10000 D This option was granted to the Reporting Person. The Reporting Person did not remit any compensation in exchange for the grant of this option. Grant to Reporting Person of an option to purchase 10,000 shares of the Issuer's common stock, par value $0.01 per share, exercisable immediately on the date of grant, subject to the Issuer's right of repurchase, which right of repurchase expires on May 6, 2005, the first anniversary of the date of grant. Mark H. Rachesky, M.D. 2004-05-07