X0202 4 2007-03-09 0000877902 NEOSE TECHNOLOGIES INC NTEC 0001207786 DOVEY BRIAN H C/O DOMAIN ASSOCIATES, LLC ONE PALMER SQUARE PRINCETON NJ 08542 1 0 0 0 Common Stock 2007-03-09 4 P 0 2418125 A 3345973 I By Domain Partners V, L.P. Common Stock 2007-03-09 4 P 0 57123 A 79041 I By DP V Associates, L.P. Warrants to Purchase Common Stock 1.96 2007-03-09 4 P 0 1088156 A 2007-03-09 2012-03-09 Common Stock 1088156 1088156 I By Domain Partners V, L.P. Warrants to Purchase Common Stock 1.96 2007-03-09 4 P 0 25705 A 2007-03-09 2012-03-09 Common Stock 25705 25705 I By DP V Associates, L.P. Units of Common Stock and Warrants were purchased at $2.02 per Unit. The Reporting Person is a managing member of One Palmer Square Associates V, L.L.C., which is the sole general partner of Domain Partners V, L.P. and DP V Associates, L.P. Pursuant to Instruction 4(b)(iv) of Form 4, the Reporting Person has elected to report as indirectly beneficially owned the entire number of securities beneficially owned by each such entity. The Reporting Person disclaims beneficial ownership of any securities, and any proceeds thereof, that exceed his or her pecuniary interest therein and/or that are not actually distributed to him or her. Kathleen K. Schoemaker, Attorney-in-Fact 2007-03-13