X0101 42003-05-13 0000877902 NEOSE TECHNOLOGIES INC NTEC0001207786 DOVEY BRIAN H 1000Stock Option (Right to Buy)9.782003-05-134A0300000A2003-05-132013-05-13Common Stock3000030000IBy Domain Associates, L.L.C.Stock Option (Right to Buy)3.262003-05-134A021470A2003-05-132013-05-13Common Stock21472147IBy Domain Associates, L.L.C.(2)Option is exercisable immediately on the date of grant subject to the Issuer's right of repurchase. The Issuer's right of repurchase expires over four successive and annual installments of 7,500 each, on the first, second, third and fourth anniversaries of the date of grant.The reporting person is one of the managing members of Domain Associates, L.L.C. Pursuant to Instruction 4(b)(iv) of Form 4, the reporting person has elected to report as indirectly beneficially owned the entire number of securities beneficially owned by Domain Associates, L.L.C. The reporting person disclaims beneficial ownership of any securities, and any proceeds thereof, that exceed his pecuniary interest therein, and/or that are not actually distributed to him.Kathleen K. Schoemaker, Attorney-in-Fact2003-05-14