X0202 4 2007-05-15 0 0000877357 SEPRACOR INC /DE/ SEPR 0001251553 SOUTHWELL DAVID P 350 MAIN ST CONCORD MA 01742 0 1 0 0 Chief Financial Officer Sepracor Common Stock 2007-05-15 4 A 0 17500 53.35 A 59702 I see footnote Sepracor Common Stock Option 53.35 2007-05-15 4 A 0 25000 53.35 A 2012-05-15 2017-05-14 Sepracor Common Stock 25000 757750 D Grant of restricted stock with three year vesting. Beneficial ownership of non-derivative securities after all transactions reported on this Form 4 is as follows: 35,523 shares - direct ownership 23,721 shares - indirect ownership; held in trust for children 458 shares - indirect ownership; held by children. Grant of stock option with five year vesting. Robyn McLaren, by power of attorney 2007-05-17