X0202 5 2005-12-31 0 0 0 0000877357 SEPRACOR INC /DE/ SEPR 0001251553 SOUTHWELL DAVID P 350 MAIN ST CONCORD MA 01742 0 1 0 0 Chief Financial Officer Sepracor Common Stock 2005-12-06 5 G 0 L 25343 56.11 D 26902 D 26,052 shares are owned directly by the Registrant. 392 shares are held in trust for Registrant's children. 458 shares are owned by Registrant's children. Robyn McLaren, by power of attorney 2006-07-27