X0202 4 2004-05-11 0 0000877357 SEPRACOR INC /DE/ SEPR 0001251553 SOUTHWELL DAVID P 350 MAIN ST CONCORD MA 01742 0 1 0 0 Executive VP and CFO Sepracor Common Stock 2004-05-11 4 S 0 2900 46.27 D 773785 D Sepracor Common Stock 2004-05-11 4 S 0 11400 46.29 D 762385 D Sepracor Common Stock 2004-05-11 4 S 0 4000 46.3 D 758385 D Sepracor Common Stock 2004-05-11 4 S 0 11700 46.31 D 746685 D Sepracor Common Stock 2004-05-11 4 S 0 625 46.32 D 746060 D Sepracor Common Stock 2004-05-11 4 S 0 600 46.33 D 745460 D Sepracor Common Stock 2004-05-11 4 S 0 3275 46.34 D 742185 D Sepracor Common Stock 2004-05-11 4 S 0 5500 46.35 D 736685 D Sepracor Common Stock 2004-05-11 4 S 0 200 46.36 D 736485 D Sepracor Common Stock 2004-05-11 4 S 0 2400 46.38 D 734085 D Sepracor Common Stock 2004-05-11 4 S 0 100 46.39 D 733985 D Sepracor Common Stock 2004-05-11 4 S 0 7881 46.4 D 726104 D Sepracor Common Stock 2004-05-11 4 S 0 200 46.41 D 725904 D Sepracor Common Stock 2004-05-11 4 S 0 8119 46.43 D 717785 D Sepracor Common Stock 2004-05-11 4 S 0 8983 46.44 D 708802 D Sepracor Common Stock 2004-05-11 4 S 0 5200 46.45 D 703602 D Sepracor Common Stock 2004-05-11 4 S 0 500 46.49 D 703102 D Sepracor Common Stock 2004-05-11 4 S 0 200 46.5 D 702902 D Sepracor Common Stock 2004-05-11 4 S 0 1548 46.51 D 701354 D Sepracor Common Stock 2004-05-11 4 S 0 5000 46.52 D 696354 D Sepracor Common Stock 2004-05-11 4 S 0 5100 46.53 D 691254 D Sepracor Common Stock 2004-05-11 4 S 0 6000 46.54 D 685254 D Sepracor Common Stock 2004-05-11 4 S 0 5300 46.55 D 679954 D Sepracor Common Stock 2004-05-11 4 S 0 1700 46.57 D 678254 D Sepracor Common Stock 2004-05-11 4 S 0 5208 46.59 D 673046 D Sepracor Common Stock 2004-05-11 4 S 0 3713 46.6 D 669333 D Sepracor Common Stock 2004-05-11 4 S 0 100 46.61 D 669233 D Sepracor Common Stock 2004-05-11 4 S 0 875 46.62 D 668358 D Sepracor Common Stock 2004-05-11 4 S 0 700 46.64 D 667658 D Sepracor Common Stock 2004-05-11 4 S 0 3769 46.65 D 663889 D Total number of shares sold reported on this Form 4 is 112,796 Robyn McLaren, by power of attorney 2004-05-12