Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 30, 2016
Operating Activities
Net loss	$ (68,640)	$ (105,988)
Adjustments to reconcile net loss to net cash and cash equivalents used in operating activities:
Depreciation	1,816	1,498
Amortization of intangible assets	5,144	5,312
Amortization of debt discount and debt issuance costs	212	140
Stock-based compensation	5,321	3,858
Non-employee warrant awards	571
Common stock issued for services		116
Inventory write-down related to restructuring		2,565
Non-cash restructuring and other charges		2,551
Goodwill impairment		61,784
Deferred tax benefit	(2,320)	(4,725)
Loss on extinguishment of debt	308
Change in fair value of warrant liabilities	25,213
Change in fair value of contingent consideration	1,226	1,700
Changes in operating assets and liabilities:
Accounts receivable	886	(809)
Interest receivable	79	(9)
Inventories	(3,519)	(1,883)
Other current and long term assets	(2,454)	(1,290)
Accounts payable	(1,599)	(1,917)
Accrued expenses	207	(168)
Net cash and cash equivalents used in operating activities	(37,549)	(37,265)
Investing Activities
Purchase of property and equipment	(1,488)	(878)
Purchase of intellectual property	(418)
Net cash and cash equivalents used in investing activities	(1,906)	(878)
Financing Activities
Payment of debt	(13,343)	(4,972)
Proceeds from issuance of debt and warrants, net of issuance costs	12,956
Payment of contingent consideration	(395)
Proceeds from issuance of common stock and warrants, net of issuance costs	31,546	57,637
Taxes paid related to net share settlement of vesting of restricted stock units	(168)	(130)
Proceeds from exercise of stock options and warrants	5,449	163
Net cash and cash equivalents provided by financing activities	36,045	52,698
Effect of exchange rate changes on cash and cash equivalents	(311)	(133)
Net (decrease) increase in cash, cash equivalents and restricted cash	(3,721)	14,422
Cash, cash equivalents and restricted cash, beginning of period	34,590	38,449
Cash, cash equivalents and restricted cash, end of period	30,869	52,871
Supplemental Disclosure for Cash Flow Information
Interest paid	597	1,019
Supplemental Schedule of Noncash Investing Activities
Transfer of inventory to property and equipment		$ 1,866
Issuance of common stock as contingent consideration	5,227
Relative fair value of warrants issued with debt	300
Reclass of warrant liability to common stock and additional paid in capital	$ 2,289