X0306 4 2016-10-19 0 0000876343 BIOTIME INC BTX 0001690272 KNIGHT JAMES A. 1010 ATLANTIC AVENUE SUITE 102 ALAMEDA CA 94501 0 1 0 0 Sr VP, Head of Corporate Dev Option to Purchase Common Shares 3.49 2016-10-19 4 A 0 300000 0.00 A 2026-10-18 Common Shares 300000 300000 D One quarter of the options shall vest on October 18, 2017, subject to the completion of 12 months of continuous employment from the date of grant on October 19, 2016, and the balance shall vest in 36 monthly installments upon the completion of each month of continuous employment from the first anniversary of the date of grant. /s/James A. Knight 2016-11-18