X0202 5 2005-12-31 0 0 0 0000876343 BIOTIME INC BTIM 0001067403 NICKEL JEFFREY B 6121 HOLLIS STREET EMERYVILLE CA 94608 0 1 0 0 Vice President Common Shares, no par value 172812 D Option to Purchase Common Shares 7.25 2001-03-26 2006-03-25 Common Shares 10000 10000 D Option to Purchase Common Shares 3.00 2007-03-30 Common Shares 20000 20000 D Option to Purchase Common Shares 1.55 2008-03-30 Common Shares 20000 20000 D Warrants to Purchase Common Shares 2.00 2010-10-31 Common Shares 937 937 D Option to Purchase Common Shares 2.17 2004-01-21 2009-03-07 Common Shares 10000 10000 D Option to Purchase Common Shares 2.00 2009-05-31 Common Shares 100000 100000 D Includes 160,000 shares that Dr. Nickel may acquire through the exercise of stock options and 937 shares that he may acquire upon the exercise of certain warrants. 12,500 options became exercisable on March 31, 2002 and the remaining 7,500 became exercisable in 9 equal monthly installments based upon continued service on the board of directors. 5,000 options became exercisable on March 31, 2003 and the remaining 15,000 became exercisable in 9 equal monthly installments based upon continued service on the board of directors. 5,000 options became exercisable on March 31, 2004 and the remaining 5,000 became exercisable on May 31, 2004. 25,000 options became exercisable on June 1, 2004 and the remaining 75,000 will become exercisable in three equal yearly installments. /s/ Jeffrey B. Nickel 2006-02-14