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Stock Option Plans (Tables)
12 Months Ended
Dec. 31, 2015
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of stock option activity
The following table summarizes stock-based compensation expense related to employee and director stock options awards for the years ended December 31, 2015, 2014, and 2013, which was allocated as follows (in thousands):
 
 
Year Ended December 31,
 
  
2015
  
2014
  
2013
 
Research and Development
 
$
3,267
  
$
1,310
  
$
830
 
General and Administrative
  
7,794
   
3,145
   
2,215
 
All stock-based compensation expense included in expenses
 
$
11,061
  
$
4,455
  
$
3,045
 

Schedule of weighted average assumptions to calculate fair value of stock options
The weighted-average estimated fair value of stock options granted under BioTime’s 2002 Plan and 2012 Plan during the years ended December 31, 2015 and 2014 was $3.72 and $3.43 per share respectively, using the Black-Scholes Merton model with the following weighted-average assumptions:
 
  
Year Ended
December 31,
 
  
2015
  
2014
 
Expected life (in years)
  
5.62
   
6.67
 
Risk-free interest rates
  
1.70%
  
2.19%
 
Volatility
  
65.82%
 
  
83.20%
 
Dividend yield
  
0.00%
 
  
0.00%
 
 
Additional information regarding options outstanding
Additional information regarding options outstanding under BioTime’s 2002 Plan and 2012 Plan as of December 31, 2015 is as follows (in thousands except exercise prices and weighted average exercise price):

     
Options Outstanding
  
Options Exercisable
 
              
Range of
Exercise
Prices
  
Number
Outstanding
 
Weighted Avg.
Remaining
Contractual Life
(years)
 
Weighted Avg.
Exercise Price
  
Number
Exercisable
 
Weighted Avg.
Exercise Price
 
 
2.52-3.96
  
3,196
  
7.08
 $
3.53
   
1,165
 $
3.47
 
 
4.02-4.95
  
1,628
  
5.30
 $
4.33
   
   962
 $
4.26
 
 
5.02-8.58
  
   370
  
1.13
 $
6.12
   
   361
 $
6.15
 
 
$2.52-8.58
  
5,194
  
6.10
 $
3.93
   
2,488
 $
4.16
 
 
2002 Plan and 2012 Plan [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Summary of stock option activity
A summary of all option activity under BioTime’s 2002 Plan and 2012 Plan for the years ended December 31, 2015 and 2014 is as follows (in thousands except weighted average exercise price):

  
Options
Available for
Grant
 
Number of
Options
Outstanding
 
Weighted
Average
Exercise
Price
 
January 1, 2014
  
2,315
   
4,567
  
$
2.71
  
Granted under 2012 Plan
  
(2,170
)
  
2,170
   
3.54
  
Exercised
  
-
   
(2,060
)
  
0.58
  
Forfeited/expired under 2002 Plan
  
-
   
(179
)
  
4.32
  
Forfeited/expired under 2012 Plan
  
523
   
(524
)
  
3.72
  
December 31, 2014
  
668
   
3,974
  
$
4.04
  
Increase in option pool
  
6,000
   
-
   
-
  
Granted under 2012 Plan
  
(1,650
)
  
1,650
   
3.72
  
Exercised
  
-
   
(156
)
  
4.00
  
Forfeited/cancelled/expired under 2002 Plan
  
-
   
(35
)
  
6.72
  
Forfeited/cancelled/expired under 2012 Plan
  
239
   
(239
)
  
3.82
  
December 31, 2015
  
5,257
   
5,194
  
$
3.93
  

Asterias Biotherapeutics [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of share-based compensation, employee stock purchase plan, activity
A summary of Asterias’ Equity Incentive Plan activity follows (in thousands, except weighted average exercise price):

  
Options and
Restricted
Stock Available
for Grant
 
Number of
Options and
Restricted Stock
Outstanding
  
Weighted
Average
Exercise
Price
 
January 1, 2014
  
1,660
  
2,840
  
$
2.34
 
Options granted
  
(1,590
)
 
1,590
   
2.50
 
Restricted stock units issued
  
(400
)
 
200
   
2.34
 
Options exercised
     
(3
)
  
2.34
 
Options expired/forfeited
  
1,280
  
(1,280
)
  
2.34
 
December 31, 2014
  
950
  
3,347
   
2.42
 
Increase in option pool
  
3,500
  
-
   
-
 
Options granted
  
(2,005
 
2,005
   
3.81
 
Options exercised
  
-
 
(13
)
  
2.34
 
Options forfeited/cancelled
  
9
  
(9
)
  
3.22
 
Restricted stock vested
     
(200
)
  
2.34
 
Restricted stock units issued
  
(388
) 
194
   
3.90
 
Restricted stock units vested
     
(145
)
  
3.90
 
Restricted stock units forfeited
  
1
  
(1
)
  
3.90
 
December 31, 2015
  
2,067
  
5,178
  
$
2.94
 
 
OrthoCyte Corporation [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of share-based compensation, employee stock purchase plan, activity
A summary of OncoCyte’s Stock Option Plan activity follows (in thousands except weighted average exercise price):

  
Options
Available
for Grant
 
Number of
Options
Outstanding
  
Weighted
Average
Exercise
Price
 
January 1, 2014
  
1,250
  
2,750
  
$
0.76
 
Options forfeited/cancelled
  
28
  
(28
)
  
1.00
 
December 31, 2014
  
1,278
  
2,722
   
0.76
 
Increase in option pool
  
4,000
  
-
   
-
 
Options granted
  
(2,875
)
 
2,875
   
1.10
 
Options exercised
  
-
 
(6
)
  
0.67
 
Options forfeited/cancelled
  
1,121
  
(1,121
)
  
0.79
 
2 for 1 reverse stock split
  
(1,762
)
 
(2,235
)
  
2.02
 
Options granted after reverse stock split
  
(10
)
 
10
   
3.60
 
Options forfeited/cancelled after reverse stock split
  
5
  
(5
)
  
2.00
 
December 31, 2015
  
1,757
  
2,240
  
$
2.94
 
 
A summary of OrthoCyte’s Stock Option Plan activity follows (in thousands except weighted average exercise price):

  
Options
Available
for Grant
  
Number of
Options
Outstanding
  
Weighted
Average
Exercise
Price
 
December 31, 2014(1)
  
1,355
   
2,645
  
$
0.08
 
Options forfeited/cancelled
  
16
   
(16
)
  
0.07
 
December 31, 2015
  
1,371
   
2,629
  
$
0.08
 
 
(1)There was no grant activity during 2014.

ReCyte Therapeutics, Inc. [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of share-based compensation, employee stock purchase plan, activity
A summary of ReCyte’s Stock Option Plan activity follows (in thousands except weighted average exercise price):
 
  
Options
Available
for Grant
  
Number of
Options
Outstanding
  
Weighted
Average
Exercise
Price
 
December 31, 2014(1)
  
2,710
   
1,290
  
$
2.05
 
Options forfeited/cancelled
  
11
   
(11
)
  
2.05
 
December 31, 2015
  
2,721
   
1,279
  
$
2.05
 
 
(1)There was no grant activity during 2014.

LifeMap Sciences, Inc. [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of share-based compensation, employee stock purchase plan, activity
A summary of LifeMap Sciences’ Equity Incentive Plan activity follows (in thousands except weighted average exercise price):
 
  
Options
Available
for Grant
  
Number of
Options
Outstanding
  
Weighted
Average
Exercise
Price
 
January 1, 2014
  
413
   
1,929
  
$
1.49
 
Options forfeited/cancelled
  
58
   
(58
)
  
1.48
 
December 31, 2014
  
471
   
1,871
   
1.48
 
Options granted
  
(131
)
  
131
   
1.92
 
Options forfeited/cancelled
  
207
   
(207
)
  
1.79
 
December 31, 2015
  
547
   
1,795
  
$
1.47
 
 
LifeMap Solutions, Inc [Member]  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Schedule of share-based compensation, employee stock purchase plan, activity
A summary of LifeMap Solutions’ Equity Incentive Plan activity follows (in thousands except weighted average exercise price):
 
  
Options
Available
for Grant
  
Number of
Options
Outstanding
  
Weighted
Average
Exercise
Price
 
Option pool added upon incorporation
  
19
     $  
Options granted
  
(13
)
  
13
   
500.00
 
December 31, 2014
  
6
   
13
   
500.00
 
Options granted
  
(2
)
  
2
   
500.00
 
Options forfeited/cancelled
  
1
   
(1
)
  
500.00
 
December 31, 2015
  
5
   
14
  
$
500.00