X0306 4 2016-08-23 0000875622 BIOSPECIFICS TECHNOLOGIES CORP BSTC 0001355189 Wegman Thomas C/O BIOSPECIFICS TECHNOLOGIES CORP., 35 WILBUR STREET LYNBROOK NY 11563 1 1 1 0 President Common Stock, $0.001 par value 2016-08-23 4 S 0 4100 38.6048 D 191722 D Common Stock, $0.001 par value 2016-08-24 4 S 0 4173 38.0773 D 187549 D The selling price of $38.6048 is reflective of the weighted average sale price of all transactions reported on this line. The prices for the transactions reported on this line range from $38.13 to $39.11. The reporting person undertakes to provide, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price. The selling price of $38.0773 is reflective of the weighted average sale price of all transactions reported on this line. The prices for the transactions reported on this line range from $38.00 to $38.25. The reporting person undertakes to provide, upon request by the staff of the Securities and Exchange Commission, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each separate price. /s/ Carl A. Valenstein, attorney-in-fact for Thomas Wegman 2016-08-24