Stock-based Compensation Expense (Tables)

12 Months Ended

Dec. 31, 2011

Stock-based Compensation Expense

Stock-based compensation expense by line item

	2011		2010		2009
	(in thousands)
Stock-based compensation expense by line item:
Research and development expenses	$	75,574	$	65,198	$	64,128
Sales, general and administrative expenses		42,652		25,926		22,594
Total stock-based compensation expense included in costs and expenses	$	118,226	$	91,124	$	86,722

Stock-based compensation expense by type of award

	2011			2010		2009
	(in thousands)
Stock-based compensation expense by type of award:
Stock options	$	83,098		$	64,005	$	63,397
Restricted stock and restricted stock units		30,708			22,960		18,983
ESPP share issuances		5,462			4,159		4,342
Less stock-based compensation expense capitalized to inventories		(1,042	)		—		—
Total stock-based compensation expense included in costs and expenses	$	118,226		$	91,124	$	86,722

Unrecognized stock-based compensation expense, net of estimated forfeitures

	As of December 31, 2011
	Unrecognized Expense Net of Estimated Forfeitures		Weighted-average Recognition Period
	(in thousands)		(in years)
Type of award:
Stock options	$	139,165		2.73
Restricted stock and restricted stock units		44,744		2.25
ESPP share issuances		5,128		0.65

Schedule of assumptions used to estimate the grant date fair value of options

	2011			2010			2009
Expected stock price volatility		49.53	%		52.17	%		57.77	%
Risk-free interest rate		2.09	%		2.44	%		2.85	%
Expected term of options		5.74 years			5.71 years			6.31 years
Expected annual dividends		—			—			—

Schedule of assumptions used to estimate the grant date fair value employee stock purchase plan

	2011			2010			2009
Expected stock price volatility		51.32	%		43.92	%		54.22	%
Risk-free interest rate		0.08	%		0.24	%		0.39	%
Expected term		0.72 years			0.71 years			0.76 years
Expected annual dividends		—			—			—