Condensed Consolidated Statements of Operations (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Revenues:
Product revenues, net	$ 74,535	$ 0	$ 74,535	$ 0
Royalty revenues	10,010	7,262	16,071	13,669
Collaborative revenues	29,879	24,360	97,480	40,382
Total revenues	114,424	31,622	188,086	54,051
Costs and expenses:
Cost of product revenues	5,404	0	5,404	0
Royalty expenses	3,902	3,086	6,568	6,453
Research and development expenses	173,604	155,082	332,216	298,094
Sales, general and administrative expenses	96,663	40,915	168,186	76,467
Restructuring expense	741	2,112	1,501	2,892
Total costs and expenses	280,314	201,195	513,875	383,906
Loss from operations	(165,890)	(169,573)	(325,789)	(329,855)
Interest income	202	484	1,604	939
Interest expense	(6,962)	(3,683)	(18,963)	(7,638)
Change in fair value of derivative instruments	(2,220)	(27,234)	(7,818)	(28,723)
Loss before provision for income taxes	(174,870)	(200,006)	(350,966)	(365,277)
Provision for income taxes (Alios)	24,448		24,448
Net loss	(199,318)	(200,006)	(375,414)	(365,277)
Net loss attributable to noncontrolling interest (Alios)	(25,249)	0	(25,249)	0
Net loss attributable to Vertex	$ (174,069)	$ (200,006)	$ (350,165)	$ (365,277)
Basic net loss attributable to Vertex per common share (in dollars per share)	$ (0.85)	$ (1.00)	$ (1.72)	$ (1.83)
Diluted net loss attributable to Vertex per common share (in dollars per share)	$ (0.85)	$ (1.00)	$ (1.72)	$ (1.83)
Basic weighted-average number of common shares outstanding (in shares)	204,413	200,397	203,377	199,670
Diluted weighted-average number of common shares outstanding (in shares)	204,413	200,397	203,377	199,670