Swiss franc Switzerland, Francs Accumulated Amortization Finite-Lived Intangible Assets, Accumulated Amortization Zai Lab Limited Zai Lab Limited [Member] Zai Lab Limited Ono Pharmaceuticals Co., Ltd. Ono Pharmaceuticals Co., Ltd. [Member] Ono Pharmaceuticals Co., Ltd. Award Timing Predetermined Award Timing Predetermined [Flag] Indefinite-lived Intangible Assets [Axis] Indefinite-Lived Intangible Assets [Axis] Unrealized holding gains (losses) on marketable securities, tax OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment, Tax Entity File Number Entity File Number Additional Paid-in Capital Additional Paid-in Capital [Member] Tabular List, Table Tabular List [Table Text Block] Additional Balance Sheet & Cash Flow Information Additional Financial Information Disclosure [Text Block] Property and equipment, net Finance Lease, Right-Of-Use Asset, Gross Finance Lease, Right-Of-Use Asset, Gross Recently Adopted and Issued Accounting Standards New Accounting Pronouncements, Policy [Policy Text Block] SOFR Secured Overnight Financing Rate (SOFR) [Member] Research and development tax credits Effective Income Tax Rate Reconciliation, Tax Credit, Research, Amount Collaborative arrangement, allocation of research and development expenses, percent Collaborative Arrangement, Allocation Of Research And Development Expenses, Percent Collaborative Arrangement, Allocation Of Research And Development Expenses, Percent Adjustment to Compensation: Adjustment to Compensation [Axis] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Stock-based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Unvested Equity Awards Unvested Equity Awards [Member] Unvested Equity Awards Schedule of Indefinite-Lived Intangible Assets by Major Class [Table] Intangible Asset, Indefinite-Lived [Table] Schedule of Cash Equivalents Schedule of Cash and Cash Equivalents [Table Text Block] Total current taxes Current Income Tax Expense (Benefit) Area of real estate property (in square feet) Area of Real Estate Property Adjustment to Compensation, Amount Adjustment to Compensation Amount Concentration risk percentage Concentration Risk, Percentage Number of purchase periods Share-based Compensation Arrangement By Share-based Payment Award, Number Of Purchase Periods Share-based Compensation Arrangement By Share-based Payment Award, Number Of Purchase Periods Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Foreign-derived deduction eligible income Effective Income Tax Rate Reconciliation, FDII, Amount Percent of awards in tranche Share-Based Compensation By Share-Based Payment Award, Percent Of Awards In Tranche Share-Based Compensation By Share-Based Payment Award, Percent Of Awards In Tranche Stock options Stock options Stock options Share-Based Payment Arrangement, Option [Member] Property, Plant and Equipment [Table] Property, Plant and Equipment [Table] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration] Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration] Percentage Effective Income Tax Rate Reconciliation, Percent [Abstract] Antidilutive Securities [Axis] Antidilutive Securities [Axis] Total shareholders’ equity Beginning balance Ending balance Equity, Attributable to Parent Debt Securities, Available-for-sale [Table] Debt Securities, Available-for-Sale [Table] Fair Value by Measurement Frequency [Axis] Measurement Frequency [Axis] Other comprehensive (loss) income: Other Comprehensive Income (Loss), Net of Tax [Abstract] Insider Trading Policies and Procedures [Line Items] Schedule of Property and Equipment Property, Plant and Equipment [Table Text Block] Common stock, shares authorized (in shares) Common Stock, Shares Authorized Collaborative Arrangements by Agreement [Domain] Collaborative Arrangements by Agreement [Domain] Collaborative Arrangements by Agreement [Domain] Potential awards, percent of target shares, maximum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Maximum Share-Based Compensation By Share-Based Payment Award, Award Percentage Of Target, Maximum Recurring basis Fair Value, Recurring [Member] Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Liabilities and Shareholders’ Equity Liabilities and Equity [Abstract] State and Local Jurisdiction State and Local Jurisdiction [Member] Fair value of cash flow hedges Cash Flow Hedge Derivative Instrument Assets at Fair Value Cover [Abstract] Cover [Abstract] Cash equivalents Cash and Cash Equivalents, Fair Value Disclosure Maximum Maximum [Member] Exercisable (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Estimated Useful lives Finite-Lived Intangible Asset, Useful Life Finite-lived intangible assets, net, total Finite-Lived Intangible Assets, Net Debt securities fair value, unrealized loss position Debt Securities, Available-for-Sale, Unrealized Loss Position Restricted stock units (including PSUs) Restricted stock units (including PSUs) Restricted Stock [Member] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Schedule of Share-based Compensation Arrangements by Share-based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule of Restricted Stock and Restricted Stock Units Activity Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block] Deferred costs Deferred Costs Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Total cash equivalents and marketable securities, Gross Unrealized Losses Cash Equivalents, Debt and Equity Securities, Unrealized Loss Cash Equivalents, Debt and Equity Securities, Unrealized Loss Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Other Assets Other assets Other Assets [Member] Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Long-term marketable securities Asset Acquisition, Marketable Securities, Noncurrent Asset Acquisition, Marketable Securities, Noncurrent Income before provision for income taxes Income before provision for income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Entity Shell Company Entity Shell Company Schedule of Revenues and Property and Equipment by Location Schedule of Revenue from External Customers and Long-Lived Assets, by Geographical Areas [Table Text Block] 2029 Finance Lease And Operating Lease, Liability, Payments, Due Year Four Finance Lease And Operating Lease, Liability, Payments, Due Year Four Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Stock-based compensation expense related to inventories Share-Based Payment Arrangement, Amount Capitalized Schedule of Cash Paid for Income Taxes Schedule of Cash Flow, Supplemental Disclosures [Table Text Block] Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Line of Credit Facility [Table] Line of Credit Facility [Table] Reduction in property, plant and equipment Property, Plant and Equipment, Gross, Period Increase (Decrease) Share-based Compensation, Shares Authorized under Stock Option Plans, by Exercise Price Range [Axis] Exercise Price Range [Axis] Proceeds from upfront payment Proceeds From Upfront Payment Proceeds From Upfront Payment Letter of Credit Letter of Credit [Member] United States Income (Loss) from Continuing Operations before Income Taxes, Domestic Schedule of Stock-based Compensation Expense by Line Item Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Operating lease liabilities Other current liabilities Operating Lease, Liability, Current Interest on lease liabilities Finance Lease, Interest Expense Computers and software Software and Software Development Costs [Member] Document Fiscal Period Focus Document Fiscal Period Focus Award Timing Method Award Timing Method [Text Block] Award Type [Axis] Award Type [Axis] Hedging Relationship [Domain] Hedging Relationship [Domain] Foreign Currency Translation Adjustment Foreign Currency Forward Contract Accumulated Foreign Currency Adjustment Attributable to Parent [Member] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Research and Development Expenses Research, Development, and Computer Software, Policy [Policy Text Block] Trading Symbol Trading Symbol 2029 Lessee, Operating Lease, Liability, to be Paid, Year Four Entity Address, City or Town Entity Address, City or Town Finance leases Finance Lease, Weighted Average Discount Rate, Percent Effect of changes in exchange rates on cash Effect of Exchange Rate on Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Total deferred tax assets Deferred Tax Assets, Net of Valuation Allowance Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Statement of Income Location, Balance [Domain] Statement of Income Location, Balance [Domain] Restricted stock units (including PSUs) Unvested restricted stock units (including PSUs) Restricted Stock Units (excluding PSUs) Restricted Stock Units (RSUs) [Member] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Settlement with tax authorities Unrecognized Tax Benefits, Decrease Resulting from Settlements with Taxing Authorities Non-financial performance shares Non-Financial Performance Shares [Member] Non-Financial Performance Shares Entity Emerging Growth Company Entity Emerging Growth Company Finance leases Finance Lease, Weighted Average Remaining Lease Term Outstanding at beginning of period (in shares) Outstanding at end of period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Prepaid expenses and other current assets Restricted Cash and Cash Equivalent Indefinite-lived intangible assets (excluding goodwill) Indefinite-Lived Intangible Assets (Excluding Goodwill) Less: amount representing interest Finance Lease, Liability, Undiscounted Excess Amount Common stock, shares outstanding (in shares) Beginning balance (in shares) Ending balance (in shares) Common Stock, Shares, Outstanding Share-based Payment Arrangement, Option, Exercise Price Range [Table] Share-Based Payment Arrangement, Option, Exercise Price Range [Table] Current taxes: Current Income Tax Expense (Benefit), Continuing Operations [Abstract] Number of shares (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Nature of Operation, Product Information, Concentration of Risk [Table] Nature of Operation, Product Information, Concentration of Risk [Table] Schedule of Finite-Lived Intangible Assets, Future Amortization Expense Schedule of Finite-Lived Intangible Assets, Future Amortization Expense [Table Text Block] Derivative Instruments and Hedging Activities Disclosure [Abstract] Derivative Instruments and Hedging Activities Disclosure [Abstract] Stock-based compensation expense: Share-based Compensation Allocation [Abstract] -- None. No documentation exists for this element. -- Prepaid expenses and other current assets Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Amortized Cost Cash Equivalents And Debt Securities, Available for Sale Cash Equivalents And Debt Securities, Available for Sale Operating loss carryforwards, not subject to expiration Operating Loss Carryforwards, Not Subject To Expiration Operating Loss Carryforwards, Not Subject To Expiration Number of Shares Number of Units Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number of Shares [Roll Forward] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Restatement Determination Date Restatement Determination Date Provision for income taxes Provision for income taxes Income Tax Expense (Benefit) Basis spread on variable rate (as a percent) Debt Instrument, Basis Spread on Variable Rate Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Designated as hedging instruments Designated as Hedging Instrument [Member] Fair Value Hierarchy and NAV [Axis] Fair Value Hierarchy and NAV [Axis] Hedging Relationship [Axis] Hedging Relationship [Axis] Share Repurchase Programs Stockholders' Equity, Policy [Policy Text Block] Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Total cash received from employees as a result of employee stock option exercises Proceeds from Stock Options Exercised Equity, Class of Treasury Stock [Line Items] Equity, Class of Treasury Stock [Line Items] Unrealized (losses) gains on foreign currency forward contracts, tax Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification, Tax, Parent Less: accumulated depreciation Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, Accumulated Depreciation and Amortization Federal Income Tax Paid, Federal, after Refund Received Buildings and improvements Building and Building Improvements [Member] All Trading Arrangements All Trading Arrangements [Member] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Accrued expenses Total Accrued Liabilities, Current Stock compensation (benefit), shortfalls and cancellations Effective Income Tax Rate Reconciliation, Tax Exempt Income, Percent Class of Treasury Stock [Table] Class of Treasury Stock [Table] Legal Matters Commitments and Contingencies, Policy [Policy Text Block] Other Effective Income Tax Rate Reconciliation, Other Adjustments, Amount Beginning of the period (in shares) End of the period (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Collaborative arrangement development and regulatory potential milestone payments maximum Collaborative Arrangement Development And Regulatory Potential Milestone Payments Maximum Represents the potential milestone amount to be paid by the entity under the collaboration agreement if drug candidates are approved and commercialized. Changes in foreign exchange rates Unrecognized Tax Benefits, Decrease Resulting from Foreign Currency Translation Net cash provided by (used in) operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Effective Income Tax Rate Reconciliation [Table] Effective Income Tax Rate Reconciliation [Table] Property and equipment estimated useful life Property, Plant and Equipment, Useful Life Preferred stock, par value (in dollars per share) Preferred Stock, Par or Stated Value Per Share Revenues from External Customers and Long-Lived Assets [Line Items] Revenues from External Customers and Long-Lived Assets [Line Items] Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] PEO Total Compensation Amount PEO Total Compensation Amount Foreign Income Tax Paid, Foreign, after Refund Received [Abstract] Depreciation expense Depreciation 2029 Finance Lease, Liability, to be Paid, Year Four Number of optional renewal terms Lessee, Operating Lease, Number Of Renewal Options Lessee, Operating Lease, Number Of Renewal Options Total liabilities Gross Amounts Recognized Derivative Liability, Subject to Master Netting Arrangement, before Offset Equity Components [Axis] Equity Components [Axis] Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Sublease income Sublease Income Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Financial performance shares Financial Performance Shares [Member] Financial Performance Shares Product revenues, net Products Product [Member] Contingent consideration, measurement input (percent) Business Combination, Contingent Consideration, Liability, Measurement Input Deferred tax assets: Components of Deferred Tax Assets [Abstract] Advertising Costs Advertising Cost [Policy Text Block] Entity Address, State or Province Entity Address, State or Province Payments on finance leases Financing cash flows from finance leases Finance Lease, Principal Payments Antidilutive Security, Excluded EPS Calculation [Table] Antidilutive Security, Excluded EPS Calculation [Table] Euro Euro Member Countries, Euro Total current liabilities Liabilities, Current Subpart F income, net of credits Effective Income Tax Rate Reconciliation, Cross-Border, Subpart F Income, Net Of Credits, Percent Effective Income Tax Rate Reconciliation, Cross-Border, Subpart F Income, Net Of Credits, Percent Individual: Individual [Axis] Defined contribution plan, cost Defined Contribution Plan, Cost Total property and equipment, gross Property, Plant, and Equipment and Finance Lease Right-of-Use Asset, before Accumulated Depreciation and Amortization Subpart F income, net of credits Effective Income Tax Rate Reconciliation, Cross-Border, Subpart F Income, Net Of Credits, Amount Effective Income Tax Rate Reconciliation, Cross-Border, Subpart F Income, Net Of Credits, Amount Income Tax Jurisdiction [Domain] Income Tax Jurisdiction [Domain] Document Annual Report Document Annual Report Research and development expenses Research and Development Expense [Member] Net payments related to finite-lived intangible assets Proceeds From (Payments For) Finite-Lived Intangible Assets Proceeds From (Payments For) Finite-Lived Intangible Assets Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] R&D capitalization Deferred Tax Asset, In-Process Research and Development Entity Interactive Data Current Entity Interactive Data Current Weighted-average Grant-date Fair Value Weighted-average Grant-date Fair Value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Additional Disclosures [Abstract] Assembled Workforce Employment Contracts [Member] Options outstanding and exercisable, weighted-average remaining contractual life Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Remaining Contractual Term Revenue Recognition Revenue from Contract with Customer [Policy Text Block] Exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Marketable securities: Marketable Securities Laboratory equipment, other equipment and furniture Laboratory equipment, other equipment and furniture Laboratory Equipment, Other Equipment and Furniture [Member] Laboratory Equipment, Other Equipment and Furniture Property, Plant and Equipment, Type [Axis] Long-Lived Tangible Asset [Axis] Long-Lived Tangible Asset [Axis] Operating lease assets Deferred Tax Assets, Operating Lease Assets Deferred Tax Assets, Operating Lease Assets Long-term marketable securities Marketable Securities, Noncurrent 2027 Finance Lease, Liability, to be Paid, Year Two Goodwill Goodwill and Intangible Assets, Goodwill, Policy [Policy Text Block] Impairment, intangible asset, indefinite-lived (excluding goodwill), statement of income or comprehensive income [extensible enumeration] Impairment, Intangible Asset, Indefinite-Lived (Excluding Goodwill), Statement of Income or Comprehensive Income [Extensible Enumeration] Weighted-average discount rate Weighted Average Discount Rate [Abstract] Weighted Average Discount Rate [Abstract] Other assets Other Assets, Noncurrent Customer [Domain] Customer [Domain] Entity Central Index Key Entity Central Index Key PEO Name PEO Name Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Other long-term liabilities, Contingent consideration Contingent consideration Business Combination, Contingent Consideration, Liability, Noncurrent Schedule of Segment Reporting Information, by Segment [Table] Schedule of Segment Reporting Information, by Segment [Table] Tranche one Share-Based Payment Arrangement, Tranche One [Member] Intangible assets Deferred Tax Assets Intangibles The component of income tax expense for the period representing the increase (decrease) in the entity's deferred tax assets related to intangible assets. Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Work-in-process Inventory, Work in Process, Net of Reserves Exercise Price Award Exercise Price Entity Filer Category Entity Filer Category Federal statutory tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Fair Value Debt And Equity Securities, Fair Value Debt And Equity Securities, Fair Value Remaining milestone payment Business Combination, Remaining Milestone Payment Business Combination, Remaining Milestone Payment 2028 Finite-Lived Intangible Asset, Expected Amortization, Year Three Statement of Financial Position Location, Balance [Axis] Statement of Financial Position Location, Balance [Axis] Vesting [Domain] Vesting [Domain] Finite-lived intangible assets, gross Finite-Lived Intangible Assets, Gross Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Entity Address, Address Line One Entity Address, Address Line One Research expenses Research Expenses Research Expenses Research and development expenses Research and Development Expense Schedule of Stock Options Outstanding and Exercisable Share-Based Payment Arrangement, Option, Exercise Price Range [Table Text Block] Accumulated Other Comprehensive Income (Loss) Total AOCI Attributable to Parent [Member] Accrued expenses Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Common stock withheld for employee tax obligations (in shares) Share-Based Payment Arrangement, Shares Withheld for Tax Withholding Obligation Increase in unrecognized tax benefits Unrecognized Tax Benefits, Period Increase (Decrease) Fair Value of Contingent Consideration In-process Research and Development Assets and Contingent Payments [Policy Text Block] Disclosure of accounting policy for costs assigned to identifiable tangible and intangible assets and contingent payments of an acquired entity to be used in the research and development activities of the combined enterprise. Common stock, number of votes per share Common Stock, Votes Per Each Share Common Stock, Votes Per Each Share Hedging Derivative Instruments and Hedging Activities Disclosure [Text Block] Exercise price, low end of range (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Lower Range Limit Name of Property [Domain] Name of Property [Domain] Fair Value as of Grant Date Award Grant Date Fair Value Amortized Cost Original cost Equity Securities, FV-NI, Cost Operating loss carryforwards Operating Loss Carryforwards Number of leases Lease Agreement, Number of Leases Represents the number of leases entered by the reporting entity. Changes in unrecognized tax benefits Effective Income Tax Rate Reconciliation, Tax Contingency, Amount Net payments due to CRISPR Therapeutics AG related to finite-lived intangible assets Noncash Financing Or Investing Activities, Collaborative Arrangement, Milestone Payments Due Noncash Financing Or Investing Activities, Collaborative Arrangement, Milestone Payments Due Derivative Instruments and Hedging Activities Disclosures [Table] Derivative Instruments and Hedging Activities Disclosures [Table] Share-based payment arrangements (in shares) Incremental Common Shares Attributable to Dilutive Effect of Share-Based Payment Arrangements Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Total costs and expenses Costs and Expenses Unrecognized Expense Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount Cancelled (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Additional In-License Agreements and Other Arrangements Additional In-License Agreements and Other Arrangements [Member] Additional In-License Agreements and Other Arrangements Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] 2027 Lessee, Operating Lease, Liability, to be Paid, Year Two Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Outstanding (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Title Trading Arrangement, Individual Title Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Non-PEO NEO Non-PEO NEO [Member] Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Allowance for credit loss for available-for-sale debt securities Debt Securities, Available-for-Sale, Allowance for Credit Loss Operating Loss and Tax Credit, Carryforwards [Table] Operating Loss and Tax Credit, Carryforwards [Table] Schedule reflecting pertinent information, such as tax authority, amounts, and expiration dates, of net operating loss carryforwards, including an assessment of the likelihood of utilization and tax credit carryforwards. Schedule of Prepaid, and Other Assets Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block] Contingent liabilities Contingent Liabilities Amount of material contingent liabilities outstanding Operating lease liabilities Deferred Tax Liabilities, Leasing Arrangements Accumulated Other Comprehensive Income (Loss) [Line Items] Accumulated Other Comprehensive Income (Loss) [Line Items] Land Land [Member] Gross Unrealized Gains Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Entrada Therapeutics Entrada Therapeutics [Member] Entrada Therapeutics Schedule of Offsetting Assets Offsetting Assets [Table Text Block] Unrecognized tax benefits, deferred tax liabilities, gross Unrecognized Tax Benefits, Deferred Tax Liabilities, Gross Unrecognized Tax Benefits, Deferred Tax Liabilities, Gross Award Type [Domain] Award Type [Domain] 2026 Lessee, Operating Lease, Liability, to be Paid, Year One Equity Awards Adjustments Equity Awards Adjustments [Member] Leasehold improvements Leasehold Improvements [Member] Advertising expense Advertising Expense Other non-cash items, net Other Noncash Income (Expense) Nonemployee Stock Option Nonemployee Stock Option [Member] Nonemployee Stock Option Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] Compensation Amount Outstanding Recovery Compensation Amount Deferred taxes: Deferred Income Tax Expense (Benefit), Continuing Operations [Abstract] Certificates of deposit Certificates of Deposit [Member] Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Revenues related to performance obligations Contract with Customer, Liability, Revenue Recognized Accredo Health Group, Inc. Accredo Health Group, Inc. [Member] Accredo Health Group, Inc. MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Statutory tax rate difference Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent Change in fair value of contingent consideration Increase in fair value of contingent payments Business Combination, Contingent Consideration, Change in Contingent Consideration, Liability, Increase (Decrease) ESPP share issuances Employee Stock [Member] Share Repurchase Program 2023 Share Repurchase Program 2023 [Member] Share Repurchase Program 2023 Indemnification claims Indemnification Claims Amount of indemnification claims currently outstanding Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Duncan McKechnie [Member] Duncan McKechnie Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible List] Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration] Commitments and Contingencies Commitments Disclosure [Text Block] Gross Amounts Not Offset Derivative Liability, Subject to Master Netting Arrangement, Deduction of Financial Instrument Not Offset Accumulated other comprehensive (loss) income Accumulated Other Comprehensive Income (Loss), Net of Tax Changes in foreign exchange rates Unrecognized Tax Benefits, Increase Resulting from Foreign Currency Translation Lonza Portsmouth Lonza Portsmouth [Member] Lonza Portsmouth Debt covenant, increase in consolidated leverage ratio Debt Covenant, Increase In Consolidated Leverage Ratio Debt Covenant, Increase In Consolidated Leverage Ratio Schedule of Cash Equivalents and Available-for-sale Securities [Table] Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Table] Schedule of the cash and cash equivalents and available-for-sale investments held by the entity. Financial Instruments [Domain] Financial Instruments [Domain] Total deferred tax liabilities Deferred Tax Liabilities, Gross Long-term marketable securities Marketable Securities Noncurrent [Member] Marketable Securities Noncurrent Schedule of Indefinite-Lived Intangible Assets Schedule of Indefinite-Lived Intangible Assets [Table Text Block] Performance-based RSUs Performance Shares [Member] Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Expected annual dividends Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Payments Royalty Royalty [Member] Other Effective Income Tax Rate Reconciliation, Nondeductible Expense, Other, Amount Less: amount representing interest Finance Lease And Operating Lease, Liability, Undiscounted Excess Amount Finance Lease And Operating Lease, Liability, Undiscounted Excess Amount Inventories Total Inventory, Net Finite-Lived Intangible Assets by Major Class [Axis] Finite-Lived Intangible Assets by Major Class [Axis] Legal Offset Derivative Asset, Subject to Master Netting Arrangement, after Offset and Deduction Minimum Minimum [Member] Deferred tax asset Asset Acquisition, Deferred Tax Asset Asset Acquisition, Deferred Tax Asset Company Selected Measure Name Company Selected Measure Name JOURNAVX JOURNAVX [Member] JOURNAVX Cost of Sales Cost of Goods and Service [Policy Text Block] Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Accounts payable Accounts Payable, Current Operating cash flows from operating leases Operating Lease, Payments Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] Foreign Current Foreign Tax Expense (Benefit) Tranche two Share-Based Payment Arrangement, Tranche Two [Member] Derivative Liability, Current, Statement of Financial Position [Extensible Enumeration] Derivative Liability, Current, Statement of Financial Position [Extensible Enumeration] Diluted (in shares) Diluted weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Diluted Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Derivative [Table] Derivative [Table] Entity Small Business Entity Small Business Cloud computing service contracts Capitalized Computer Software, Gross Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Unrecognized tax benefits, income tax penalties and interest expense (credit) Unrecognized Tax Benefits, Income Tax Penalties and Interest Expense Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding State Current State and Local Tax Expense (Benefit) Document Transition Report Document Transition Report Matures after one year through five years Debt Securities, Available-for-Sale, Fair Value, Maturity, Allocated and Single Maturity Date, after Year One Through Five Schedule of Significant Customers Schedules of Concentration of Risk, by Risk Factor [Table Text Block] Total lease payments Finance Lease, Liability, to be Paid Underlying Securities Award Underlying Securities Amount Moderna Agreement Moderna Agreement [Member] Moderna Agreement [Member] Summary of Tax Credit Carryforwards Summary of Tax Credit Carryforwards [Table Text Block] Equity Component [Domain] Equity Component [Domain] Document Period End Date Document Period End Date Income Taxes Income Tax Disclosure [Text Block] United Kingdom UNITED KINGDOM Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Product revenue accruals Product Sales Accrued Liabilities Total of product sales allowances and reserves that reflect a liability established to represent expected future costs. Exercisable (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Gross Unrealized Losses Debt And Equity Securities, Unrealized Loss Debt And Equity Securities, Unrealized Loss Stock options outstanding and exercisable Share-Based Payment Arrangement, Option, Exercise Price Range [Line Items] Document Type Document Type Level 3 Fair Value, Inputs, Level 3 [Member] Earnings Per Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Product and Service [Axis] Product and Service [Axis] Schedule of Cash, Cash Equivalents and Available-for-sale Securities Schedule of Cash, Cash Equivalents and Available-for-sale Securities [Line Items] -- None. No documentation exists for this element. -- Asset Acquisition [Domain] Asset Acquisition [Domain] Variable lease cost Variable Lease, Cost Product revenues, net Total product revenues, net Total revenues Revenue from Contract with Customer, Excluding Assessed Tax Total consideration allocated Total consideration allocated Asset Acquisition, Consideration Transferred Total current assets Assets, Current Corporate Headquarters Fan Pier Leases [Member] Represents the fan pier leases. Statistical Measurement [Axis] Statistical Measurement [Axis] Loss contingencies accrued Loss Contingency Accrual Number of shares authorized to be repurchased Share Repurchase Program, Authorized, Amount Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Schedule of Unrecognized Stock-Based Compensation Expense Schedule Of Unrecognized Share-based Compensation Expense [Table Text Block] Disclosure as of the latest balance-sheet date presented of the total compensation cost related to outstanding, nonvested share-based compensation awards not yet recognized, net of estimated forfeitures, and the weighted average period over which those unrecognized costs are expected to be reported. Total intrinsic value of stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value Payments in connection with common stock withheld for employee tax obligations Payment, Tax Withholding, Share-Based Payment Arrangement Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Derivative term Derivative, Term of Contract Acquisition of available-for-sale debt securities from Alpine Immune Sciences, Inc. Payments To Acquire Debt Securities, Available-For-Sale, Asset Acquisition Payments To Acquire Debt Securities, Available-For-Sale, Asset Acquisition Marketable securities Marketable Securities, Current Share Repurchase Program [Domain] Share Repurchase Program [Domain] Current liabilities: Liabilities, Current [Abstract] Total other comprehensive (loss) income Other comprehensive (loss) income, net of tax Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent Weighted-average Exercise Price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Level 1 Fair Value, Inputs, Level 1 [Member] Diluted (in dollars per share) Diluted net income (loss) per common share (in dollars per share) Earnings Per Share, Diluted Accounts receivable, net Accounts Receivable, after Allowance for Credit Loss, Current Reclassification out of Accumulated Other Comprehensive Income [Axis] Reclassification out of Accumulated Other 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Auditor Name Auditor Name 2027 Finance Lease And Operating Lease, Liability, Payment, Due Year Two Finance Lease And Operating Lease, Liability, Payment, Due Year Two Concentration Risk [Table] Concentration Risk [Table] Nature of Business and Accounting Policies Organization, Consolidation, Basis of Presentation, Business Description and Accounting Policies [Text Block] Capital Loss Carryforward Capital Loss Carryforward [Member] Summary of Operating Loss Carryforwards Summary of Operating Loss Carryforwards [Table Text Block] Supplemental disclosure of cash flow information: Supplemental Cash Flow Information [Abstract] Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Revenue from External Customer [Line Items] Revenue from External Customer [Line Items] 2013 Stock and Option Plan Stock and Option Plan 2013 [Member] Stock and Option Plan 2013 [Member] Other Performance Measure, Amount Other Performance Measure, Amount Schedule of Restrictions on Cash and Cash Equivalents Restrictions on Cash and Cash Equivalents [Table Text Block] Marketable Securities Marketable Securities, Policy [Policy Text Block] Amount Income Tax Expense (Benefit), Effective Income Tax Rate Reconciliation, Amount [Abstract] Other current liabilities Other Current Liabilities [Member] Credit Concentration Risk Credit Concentration Risk [Member] Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Abstract] Reduction to finance leases Reduction To Finance Leases Reduction To Finance Leases Derivative Instrument [Axis] Derivative Instrument [Axis] Vesting [Axis] Vesting [Axis] Leases Lessee, Finance Leases [Text Block] Other Other Assets, Current Additional paid-in capital Additional Paid in Capital, Common Stock Corporate equity securities Equity Securities, FV-NI and without Readily Determinable Fair Value [Abstract] Entity [Domain] Entity [Domain] Net cash used in investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Other assets, Foreign currency forward contracts Derivative Asset, Noncurrent Cash paid for interest Interest Paid, Excluding Capitalized Interest, Operating Activity Document Fiscal Year Focus Document Fiscal Year Focus Collaborative Arrangements by Agreement [Axis] Collaborative Arrangements by Agreement [Axis] Significant terms of collaboration arrangements, by individual agreement. Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Operating lease assets Operating Lease, Right-of-Use Asset Provision for income taxes and effective tax rate Effective tax rate Effective Income Tax Rate Reconciliation, Percent Deferred charges related to intra-entity transfers Effective Income Tax Rate Reconciliation, Deferred Charges Related To Intra-Entity Transfers, Amount Effective Income Tax Rate Reconciliation, Deferred Charges Related To Intra-Entity Transfers, Amount Decreases related to prior period tax positions Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions Operating lease cost Operating Lease, Cost Plan Name [Domain] Plan Name [Domain] $200.01–$502.97 Exercise Price Range From Dollars 200.01 to Dollars $502.97 [Member] Exercise Price Range From Dollars 200.01 to Dollars $502.97 Weighted-average Recognition Period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Valuation allowance Valuation allowance Deferred Tax Assets, Valuation Allowance Equity [Abstract] Equity [Abstract] Buildings and improvements Building [Member] Hedging Activities Derivatives, Policy [Policy Text Block] Segment Information Segment Reporting Disclosure [Text Block] Not designated as hedging instrument Not Designated as Hedging Instrument [Member] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] U.S. Treasury securities US Treasury Securities [Member] Federal Current Federal Tax Expense (Benefit) Increase (Decrease) in Stockholders' Equity Increase (Decrease) in Stockholders' Equity [Roll Forward] Unrealized (losses) gains on foreign currency forward contracts, net of tax of $56.0, $(38.2) and $14.0, respectively Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), after Reclassification and Tax, Parent Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Beginning balance Ending balance Business Combination, Contingent Consideration, Liability Accumulated Other Comprehensive Income (Loss) Comprehensive Income (Loss) Note [Text Block] Fair Value, Recurring and Nonrecurring [Table] Fair Value, Recurring and Nonrecurring [Table] Amortization of intangible assets Amortization of Intangible Assets Leases Lessee, Leases [Policy Text Block] Selling, general and administrative expenses Selling, General and Administrative Expense Deferred tax assets Deferred Income Tax Assets, Net Repurchases of common stock Repurchases of common stock Stock Repurchased During Period, Value Schedule of Accumulated Other Comprehensive Income (Loss) Schedule of Accumulated Other Comprehensive Income (Loss) [Table Text Block] Depreciation and amortization expense Depreciation, Depletion and Amortization Royalty payable Accrued Royalties, Current Schedule of Revenues from External Customers and Long-Lived Assets [Table] Schedule of Revenues from External Customers and Long-Lived Assets [Table] Revolving Credit Facility Revolving Credit Facility [Member] Accounts Receivable Accounts Receivable [Policy Text Block] Statutory tax rate difference Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Amount Total finance lease liabilities Finance lease liabilities Finance Lease, Liability Arrangement Duration Trading Arrangement Duration Other Other Sundry Liabilities, Noncurrent Segments [Axis] Segments [Axis] Local Phone Number Local Phone Number Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Europe Europe [Member] Market share price (in dollars per share) Share Price Other investing activities Payment for (Proceeds from) Other Investing Activity Stock-based Compensation Expense Share-Based Payment Arrangement [Text Block] Schedule of Stock and Stock Equity Plans Schedule of Stock and Stock Option, Equity Plans [Table Text Block] This schedule discloses the information pertaining to stock and stock option plans relating to the entity's equity. Assets Assets [Abstract] Credit Facility [Axis] Credit Facility [Axis] 2026 Finance Lease And Operating Lease, Liability, Payment, Due Next Twelve Months Finance Lease And Operating Lease, Liability, Payment, Due Next Twelve Months Underlying Security Market Price Change Underlying Security Market Price Change, Percent Cancelled (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Fair Value Measurements Fair Value Disclosures [Text Block] Credit Facility [Domain] Credit Facility [Domain] Other current liabilities, Foreign currency forward contracts Foreign currency forward contracts Derivative Liability, Current Total other assets Asset Acquisition, Other Assets Asset Acquisition, Other Assets Collaborative arrangement, milestone payment Collaborative Arrangement, Milestone Payment Collaborative Arrangement, Milestone Payment Vesting percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Schedule of Revenues by Product Revenue from External Customers by Products and Services [Table Text Block] Long-term operating lease liabilities Operating Lease, Liability, Noncurrent Entity Voluntary Filers Entity Voluntary Filers Total assets Gross Amounts Recognized Derivative Asset, Subject to Master Netting Arrangement, before Offset Property, Plant and Equipment [Abstract] Property, Plant and Equipment [Abstract] Entity Registrant Name Entity Registrant Name Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Cloud computing service contracts, amortization Capitalized Computer Software, Amortization Awards outstanding (in shares) Share-Based Compensation Arrangement By Share-based Payment Award, Equity Instruments Outstanding, Number Share-Based Compensation Arrangement By Share-based Payment Award, Equity Instruments Outstanding, Number Total financial assets Assets, Fair Value Disclosure $86.52–$100.00 Exercise Price Range from Dollars 86.52 to Dollars 100.00 [Member] Exercise Price Range from Dollars 77.31 to Dollars 100.00 2030 Finance Lease And Operating Lease, Liability, Payments, Due Year Five Finance Lease And Operating Lease, Liability, Payments, Due Year Five Equity securities without readily determinable fair value, amount Equity Securities without Readily Determinable Fair Value, Amount Number of operating segments Number of Operating Segments Other product revenues Manufactured Product, Other [Member] Operating leases Leases, Operating [Abstract] Fair Value Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure Cash Equivalents And Debt Securities, Available for Sale, Fair Value Disclosure Tax Credit Carryforward [Line Items] Tax Credit Carryforward [Line Items] Granted (in dollars per share) Granted (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Legal Offset Derivative Liability, Subject to Master Netting Arrangement, after Offset and Deduction Other long-term liabilities Other Noncurrent Liabilities [Member] Schedule of Finite-Lived Intangible Assets, Net Schedule of Finite-Lived Intangible Assets [Table Text Block] Restatement Determination Date: Restatement Determination Date [Axis] Percentage of Accounts Receivable Accounts Receivable [Member] Foreign Deferred Foreign Income Tax Expense (Benefit) Accumulated Other Comprehensive Income (Loss) [Table] Accumulated Other Comprehensive Income (Loss) [Table] Other financing activities Proceeds from (Payment for) Other Financing Activity All Currencies [Domain] All Currencies [Domain] Weighted-average Remaining Contractual Life Weighted Average, Remaining Contractual Life [Abstract] -- None. No documentation exists for this element. -- Name Trading Arrangement, Individual Name Marketed Products Marketing-Related Intangible Assets [Member] Schedule of Supplemental Cash Flow Information Lease, Supplemental Cash Flow Information [Table Text Block] Lease, Supplemental Cash Flow Information [Table Text Block] Statement of Comprehensive Income [Abstract] Statement of Comprehensive Income [Abstract] Unrecognized tax benefits, increase (decrease) in deferred tax assets, gross Unrecognized Tax Benefits, Increase (Decrease) In Deferred Tax Assets, Gross Unrecognized Tax Benefits, Increase (Decrease) In Deferred Tax Assets, Gross Share Repurchase Program [Axis] Share Repurchase Program [Axis] Name Awards Close in Time to MNPI Disclosures, Individual Name Components of income (loss) before provision for (benefit from) income taxes Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest [Abstract] Transaction costs Asset Acquisition, Consideration Transferred, Transaction Cost Beginning of the period (in dollars per share) End of the period (in dollars per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Schedule of Finance Lease, Liability, Maturity Finance Lease, Liability, to be Paid, Maturity [Table Text Block] In-process research and development In Process Research and Development [Member] Foreign Tax Jurisdiction Foreign Tax Jurisdiction [Member] Auditor Firm ID Auditor Firm ID Segments [Domain] Segments [Domain] Statement of Income Location, Balance [Axis] Statement of Income Location, Balance [Axis] Foreign Income (Loss) from Continuing Operations before Income Taxes, Foreign Fair Value, Measurements, Fair Value Hierarchy [Domain] Fair Value Hierarchy and NAV [Domain] Commercial paper Commercial Paper, Not Included with Cash and Cash Equivalents [Member] Statement of Financial Position Location, Balance [Domain] Statement of Financial Position Location, Balance [Domain] Inventories Increase (Decrease) in Inventories Cash and cash equivalents Asset Acquisition, Cash and Equivalents Asset Acquisition, Cash and Equivalents On Available-For-Sale Debt Securities AOCI, Accumulated Gain (Loss), Debt Securities, Available-for-Sale, Parent [Member] Net Income (Loss) Per Common Share Earnings Per Share, Policy [Policy Text Block] Australian dollar Australia, Dollars $150.01–$200.00 Exercise Price Range from Dollars 150.01 to Dollars 200.00 [Member] Represents the range of exercise prices from $150.01 to $200.00 per share for the purpose of disclosing shares potentially issuable under outstanding stock options, as well as other option information. Weighted-average remaining lease term (in years) Weighted-Average Remaining Lease [Abstract] Weighted-Average Remaining Lease [Abstract] Gross Amounts Offset Derivative Liability, Subject to Master Netting Arrangement, Asset Offset Purchases of available-for-sale debt securities Payments to Acquire Debt Securities, Available-for-Sale Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Schedule Of Weighted-Average Remaining Lease Terms And Discount Rates Related To Leases [Table Text Block] Schedule of Weighted-Average Remaining Lease Terms and Discount Rates Related to Leases [Table Text Block] Preferred stock, $0.01 par value; 1,000,000 shares authorized; none issued and outstanding Preferred Stock, Value, Issued $100.01–$150.00 Exercise Price Range from Dollars 100.01 to Dollars 150.00 [Member] Represents the range of exercise prices from $100.01 to $150.00 per share for the purpose of disclosing shares potentially issuable under outstanding stock options, as well as other option information. All Executive Categories All Executive Categories [Member] Total stock-based compensation expense included in “Total costs and expenses” Share-Based Payment Arrangement, Expensed and Capitalized, Amount Schedule of Deferred Tax Assets and Liabilities Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Finished goods Inventory, Finished Goods, Net of Reserves Common stock, $0.01 par value; 500,000,000 shares authorized, 253,991,224 and 256,940,382 shares issued and outstanding, respectively Common Stock, Value, Issued Total finance lease assets Finance Lease, Right-of-Use Asset, after Accumulated Amortization Deferred income taxes Increase (Decrease) in Other Deferred Liability Total cash equivalents and marketable securities, Amortized Cost Cash Equivalents, Debt and Equity Securities, Cost Cash Equivalents, Debt and Equity Securities, Cost Concentration Risk [Line Items] Concentration Risk [Line Items] Net deferred tax assets Deferred Tax Assets, Net Capital related accruals Capital Related Accruals Capital Related Accruals Derivative Asset, Current, Statement of Financial Position [Extensible Enumeration] Derivative Asset, Current, Statement of Financial Position [Extensible Enumeration] PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Marketable Securities and Equity Investments Cash, Cash Equivalent, and Marketable Security [Text Block] CRISPR CRISPR [Member] CRISPR Hedging Designation [Axis] Hedging Designation [Axis] Schedule of Unrecognized Tax Benefits Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block] Schedule of Allocation of Consideration Assets Acquired and Liabilities Assumed Asset Acquisition [Table Text Block] Present value of lease liabilities Finance Lease And Operating Lease, Liability Finance Lease And Operating Lease, Liability Derivative Contract [Domain] Derivative Contract [Domain] All Individuals All Individuals [Member] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Name Forgone Recovery, Individual Name Expiration period Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Reclassification out of Accumulated Other Comprehensive Income Reclassification out of Accumulated Other Comprehensive Income [Member] Issuances of common stock under benefit plans Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Including Option Exercised Share-based compensation arrangement by share-based payment award, purchase price of common stock, percent Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent Issuance of common stock under benefit plans Stock Issued During Period, Value, Employee Benefit Plan Total marketable available-for-sale debt securities Marketable Securities And Other Noncurrent Assets [Member] Marketable Securities And Other Noncurrent Assets Accrued expenses Accrued Liabilities, Current [Abstract] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Line of Credit Facility [Line Items] Line of Credit Facility [Line Items] Upfront and milestone payments Collaborative Arrangement, Milestone And Upfront Payment Collaborative Arrangement, Milestone And Upfront Payment Acquired in-process research and development expense Indefinite-Lived Intangible Assets Acquired Geographical [Axis] Geographical [Axis] Lessee, Lease, Description [Line Items] Lessee, Lease, Description [Line Items] Tax-related liabilities Tax Related Liabilities, Noncurrent Tax Related Liabilities, Noncurrent Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Lease agreements number of buildings Lease Agreement, Number of Buildings Represents number of buildings under lease agreements. Gross Unrealized Gains Debt And Equity Securities, Unrealized Gain Debt And Equity Securities, Unrealized Gain Tax credit carryforwards Deferred Tax Assets, Tax Credit Carryforwards Total cash equivalents and marketable securities, Fair Value Cash Equivalents, Debt and Equity Securities, Fair Value Cash Equivalents, Debt and Equity Securities, Fair Value Net foreign currency exchange transaction losses Gain (Loss), Foreign Currency Transaction, before Tax Options outstanding and exercisable, weighted-average exercise price (in dollars per share) Share-Based Payment Arrangement, Option, Exercise Price Range, Outstanding, Weighted Average Exercise Price Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Concentration Risk Benchmark [Domain] Concentration Risk Benchmark [Domain] Title of 12(b) Security Title of 12(b) Security Lessee, Lease, Description [Table] Lessee, Lease, Description [Table] Tax Carryforwards [Line Items] Tax Carryforwards [Line Items] -- None. No documentation exists for this element. -- CRISPR Therapeutics CRISPR Therapeutics AG [Member] CRISPR Therapeutics AG Amortized Cost Debt And Equity Securities, Cost Debt And Equity Securities, Cost Allocation of net profits and net losses, percent Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent Collaborative Arrangement, Allocation Of Net Profits And Losses, Percent Net income (loss) per common share: Earnings Per Share [Abstract] 2030 Lessee, Operating Lease, Liability, to be Paid, Year Five Foreign-derived deduction eligible income Effective Income Tax Rate Reconciliation, FDII, Percent Gross Unrealized Losses Equity Securities, FV-NI, Unrealized Loss Schedule of Potential Gross Common Equivalent Shares Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Tax credit carryforwards Tax Credit Carryforward, Amount Effect of potentially dilutive securities: Weighted Average Number of Shares Outstanding, Diluted, Adjustment [Abstract] Thereafter Finance Lease, Liability, to be Paid, after Year Five Exercised (in dollars per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price TRIKAFTA/KAFTRIO TRIKAFTA/KAFTRIO [Member] TRIKAFTA/KAFTRIO Award Timing Disclosures [Line Items] Schedule of Inventories by Type Schedule of Inventory, Current [Table Text Block] Other Other Countries Outside of the United States and Europe [Member] Other Countries Outside of the United States and Europe [Member] Upfront and milestones payable Upfront And Milestones Payable, Current Upfront And Milestones Payable, Current Measurement Frequency [Domain] Measurement Frequency [Domain] Optional term of lease agreement (in years) Lessee, Operating Lease, Renewal Term Acquired in-process research and development expenses Research and Development Asset Acquired in Transaction Other than Business Combination or Joint Venture Formation, Writeoff State Deferred State and Local Income Tax Expense (Benefit) income (loss) income (loss) Net income (loss) Net Income (Loss) Attributable to Parent Other Other Accrued Liabilities, Current Schedule of Effective Income Tax Rate Reconciliation Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Vesting period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Other Effective Income Tax Rate Reconciliation, Other Adjustments, Percent Segment Reporting Information [Line Items] Segment Reporting Information [Line Items] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Repurchases of common stock Payments for Repurchase of Common Stock Adoption Date Trading Arrangement Adoption Date Base Rate Base Rate [Member] Tax Credit Carryforward [Table] Tax Credit Carryforward [Table] Lease agreement initial term Lessee, Operating Lease, Term of Contract Customer [Axis] Customer [Axis] Income (loss) from operations Operating Income (Loss) Schedule of Offsetting Liabilities Offsetting Liabilities [Table Text Block] Thereafter Finance Lease And Operating Lease, Liability, Payments, Due After Year Five Finance Lease And Operating Lease, Liability, Payments, Due After Year Five Stock-based Compensation Expense Compensation Related Costs, Policy [Policy Text Block] Retained earnings Retained Earnings (Accumulated Deficit) Name of Property [Axis] Name of Property [Axis] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Intangible asset impairment charge Intangible asset impairment charges Impairment of Intangible Assets, Indefinite-Lived (Excluding Goodwill) Maximum percentage of annual compensation contributed by the participant (percent) Defined Contribution Plan, Maximum Annual Contributions Per Employee, Percent On Foreign Currency Forward Contracts Accumulated Gain (Loss), Net, Cash Flow Hedge, Parent [Member] Other Effective Income Tax Rate Reconciliation, Cross-Border, Other, Amount Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Other Deferred Tax Liabilities, Other Other expense, net Other Nonoperating Income (Expense) Statement [Table] Statement [Table] Total deferred taxes Deferred Income Tax Expense (Benefit) Current marketable securities Asset Acquisition, Marketable Securities, Current Asset Acquisition, Marketable Securities, Current Statute of limitations expiration Unrecognized Tax Benefits, Reduction Resulting from Lapse of Applicable Statute of Limitations Cash flows from financing activities: Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Percentage of Total Gross Product Revenues Revenue Benchmark [Member] Other foreign jurisdictions Foreign Tax Jurisdiction, Other [Member] Non-deductible AIPR&D Effective Income Tax Rate Reconciliation, Nondeductible Expense, Research and Development, Percent Variable Rate [Domain] Variable Rate [Domain] Contract liabilities Contract with Customer, Liability Finance lease liabilities Finance Lease, Liability, Noncurrent All Adjustments to Compensation All Adjustments to Compensation [Member] Amendment Flag Amendment Flag Income tax effect Share-Based Payment Arrangement, Expense, Tax Benefit Number of shares authorized (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Termination Date Trading Arrangement Termination Date Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Raw materials Inventory, Raw Materials, Net of Reserves Tranche three Share-Based Payment Arrangement, Tranche Three [Member] Operating leases Operating Lease, Weighted Average Discount Rate, Percent Schedule of Outstanding and Exercisable Options Share-Based Payment Arrangement, Option, Activity [Table Text Block] Unrecognized tax benefits, income tax penalties and interest accrued Unrecognized Tax Benefits, Income Tax Penalties and Interest Accrued Selling and other commercial expenses Selling Expense Basic (in shares) Basic weighted-average common shares outstanding (in shares) Weighted Average Number of Shares Outstanding, Basic Net unrecognized tax benefits which would affect the tax rate if recognized Unrecognized Tax Benefits that Would Impact Effective Tax Rate Schedule of Computation of Basic and Diluted Net Income (Loss) Per Common Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Exercisable (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Exercise Price Range [Domain] Exercise Price Range [Domain] Segment Reporting [Abstract] Segment Reporting [Abstract] Estimated Amortization Expense Finite-Lived Intangible Assets, Net, Amortization Expense, Fiscal Year Maturity [Abstract] Less: Expense related to unvested equity awards Asset Acquisition, Expense Related To Unvested Equity Awards Asset Acquisition, Expense Related To Unvested Equity Awards Costs and expenses: Costs and Expenses [Abstract] Total liabilities Offsetting Derivative Liabilities [Abstract] Debt securities, available-for-sale, realized gain (loss) Debt Securities, Available-for-Sale, Realized Gain (Loss) Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Share-based Compensation Arrangement by Share-based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Common stock, par value (in dollars per share) Common Stock, Par or Stated Value Per Share Total revenues outside of the United States Total long-lived assets outside of the United States Outside the United States [Member] Outside the United States [Member] Derivative Instruments and Hedging Activities Disclosures [Line Items] Derivative Instruments and Hedging Activities Disclosures [Line Items] Granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Use of Estimates Use of Estimates, Policy [Policy Text Block] Operating cash flows from finance leases Finance Lease, Interest Payment on Liability Schedule of Assumptions Used to Estimate the Grant Date Fair Value Employee Stock Purchase Plan Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Options outstanding and exercisable, number outstanding (in shares) Share-Based Payment Arrangement, Option, Exercise Price Range, Shares Outstanding Gross Amounts Offset Derivative Asset, Subject to Master Netting Arrangement, Liability Offset Insider Trading Arrangements [Line Items] Corporate equity securities Equity Securities [Member] Interest income Interest income Investment Income, Interest and Dividend Collaborative arrangement, right to exclusively license, number of targets Collaborative Arrangement, Right To License, Number Of Targets Collaborative Arrangement, Right To License, Number Of Targets Total liabilities Liabilities Currency [Axis] Currency [Axis] Antidilutive Securities, Name [Domain] Antidilutive Securities, Name [Domain] Product Concentration Risk Product Concentration Risk [Member] 2030 Finance Lease, Liability, to be Paid, Year Five Acquired In-process Research and Development Expenses In Process Research and Development, Policy [Policy Text Block] Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Increases related to current period tax positions Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions Sales and maturities of available-for-sale debt securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Deferred charges related to intra-entity transfers Effective Income Tax Rate Reconciliation, Deferred Charges Related To Intra-Entity Transfers, Percent Effective Income Tax Rate Reconciliation, Deferred Charges Related To Intra-Entity Transfers, Percent Asset-backed securities Asset-Backed Securities [Member] Variable Rate [Axis] Variable Rate [Axis] CRISPR JDCA CRISPR JDCA [Member] CRISPR joint development and commercialization agreement Deferred tax liabilities: Components of Deferred Tax Liabilities [Abstract] Fair Value Total Debt Securities, Available-for-Sale Tax Credit Carryforward, Name [Domain] Tax Credit Carryforward, Name [Domain] Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Non-NEOs Non-NEOs [Member] Corporate debt securities Corporate Debt Securities [Member] Alpine Immune Sciences Inc Alphine Immune Sciences Inc [Member] Alpine Immune Sciences Inc Offering period (in months) Share-based Compensation Arrangement by Share-based Payment Award, Offering Period Share-based Compensation Arrangement by Share-based Payment Award, Offering Period Aggregate Intrinsic Value Aggregate intrinsic value [Abstract] -- None. No documentation exists for this element. --