0000001 - Document - Cover link:presentationLink link:calculationLink link:definitionLink 0000002 - Document - Audit Information link:presentationLink link:calculationLink link:definitionLink 9952151 - Statement - Consolidated Statements of Income (Loss) link:presentationLink link:calculationLink link:definitionLink 9952152 - Statement - Consolidated Statements of Comprehensive Income (Loss) link:presentationLink link:calculationLink link:definitionLink 9952153 - Statement - Consolidated Statements of Comprehensive Income (Loss) (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952154 - Statement - Consolidated Balance Sheets link:presentationLink link:calculationLink link:definitionLink 9952155 - Statement - Consolidated Balance Sheets (Parenthetical) link:presentationLink link:calculationLink link:definitionLink 9952156 - Statement - Consolidated Statements of Shareholders’ Equity link:presentationLink link:calculationLink link:definitionLink 9952157 - Statement - Consolidated Statements of Cash Flows link:presentationLink link:calculationLink link:definitionLink 9952158 - Disclosure - Nature of Business and Accounting Policies link:presentationLink link:calculationLink link:definitionLink 9952159 - Disclosure - Collaboration, License and Other Arrangements link:presentationLink link:calculationLink link:definitionLink 9952160 - Disclosure - Earnings Per Share link:presentationLink link:calculationLink link:definitionLink 9952161 - Disclosure - Fair Value Measurements link:presentationLink link:calculationLink link:definitionLink 9952162 - Disclosure - Marketable Securities and Equity Investments link:presentationLink link:calculationLink link:definitionLink 9952163 - Disclosure - Accumulated Other Comprehensive Income (Loss) link:presentationLink link:calculationLink link:definitionLink 9952164 - Disclosure - Hedging link:presentationLink link:calculationLink link:definitionLink 9952165 - Disclosure - Inventories link:presentationLink link:calculationLink link:definitionLink 9952166 - Disclosure - Property and Equipment link:presentationLink link:calculationLink link:definitionLink 9952167 - Disclosure - Goodwill and Other Intangible Assets link:presentationLink link:calculationLink link:definitionLink 9952168 - Disclosure - Additional Balance Sheet & Cash Flow Information link:presentationLink link:calculationLink link:definitionLink 9952169 - Disclosure - Leases link:presentationLink link:calculationLink link:definitionLink 9952170 - Disclosure - Common Stock, Preferred Stock and Equity Plans link:presentationLink link:calculationLink link:definitionLink 9952171 - Disclosure - Stock-based Compensation Expense link:presentationLink link:calculationLink link:definitionLink 9952172 - Disclosure - Income Taxes link:presentationLink link:calculationLink link:definitionLink 9952173 - Disclosure - Commitments and Contingencies link:presentationLink link:calculationLink link:definitionLink 9952174 - Disclosure - Segment Information link:presentationLink link:calculationLink link:definitionLink 9955511 - Disclosure - Nature of Business and Accounting Policies (Policies) link:presentationLink link:calculationLink link:definitionLink 9955512 - Disclosure - Nature of Business and Accounting Policies (Tables) link:presentationLink link:calculationLink link:definitionLink 9955513 - Disclosure - Collaboration, License and Other Arrangements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955514 - Disclosure - Earnings Per Share (Tables) link:presentationLink link:calculationLink link:definitionLink 9955515 - Disclosure - Fair Value Measurements (Tables) link:presentationLink link:calculationLink link:definitionLink 9955516 - Disclosure - Marketable Securities and Equity Investments (Tables) link:presentationLink link:calculationLink link:definitionLink 9955517 - Disclosure - Accumulated Other Comprehensive Income (Loss) (Tables) link:presentationLink link:calculationLink link:definitionLink 9955518 - Disclosure - Hedging (Tables) link:presentationLink link:calculationLink link:definitionLink 9955519 - Disclosure - Inventories (Tables) link:presentationLink link:calculationLink link:definitionLink 9955520 - Disclosure - Property and Equipment (Tables) link:presentationLink link:calculationLink link:definitionLink 9955521 - Disclosure - Goodwill and Other Intangible Assets (Tables) link:presentationLink link:calculationLink link:definitionLink 9955522 - Disclosure - Additional Balance Sheet & Cash Flow Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955523 - Disclosure - Leases (Tables) link:presentationLink link:calculationLink link:definitionLink 9955524 - Disclosure - Common Stock, Preferred Stock and Equity Plans (Tables) link:presentationLink link:calculationLink link:definitionLink 9955525 - Disclosure - Stock-based Compensation Expense (Tables) link:presentationLink link:calculationLink link:definitionLink 9955526 - Disclosure - Income Taxes (Tables) link:presentationLink link:calculationLink link:definitionLink 9955527 - Disclosure - Segment Information (Tables) link:presentationLink link:calculationLink link:definitionLink 9955528 - Disclosure - Nature of Business and Accounting Policies - Revenue Recognition (Details) link:presentationLink link:calculationLink link:definitionLink 9955529 - Disclosure - Nature of Business and Accounting Policies - Advertising Costs (Details) link:presentationLink link:calculationLink link:definitionLink 9955530 - Disclosure - Nature of Business and Accounting Policies - schedule of Property and Equipment (Details) link:presentationLink link:calculationLink link:definitionLink 9955531 - Disclosure - Nature of Business and Accounting Policies - Goodwill, Hedging Activities and Foreign Currency Gain (Loss) (Details) link:presentationLink link:calculationLink link:definitionLink 9955532 - Disclosure - Collaboration, License and Other Arrangements - Narrative (Details) link:presentationLink link:calculationLink link:definitionLink 9955533 - Disclosure - Collaboration, License and Other Arrangements - Allocation of Consideration to the Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955534 - Disclosure - Earnings Per Share - Schedule of Computation (Details) link:presentationLink link:calculationLink link:definitionLink 9955535 - Disclosure - Earnings Per Share - Schedule of Anti-dilutive Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955536 - Disclosure - Fair Value Measurements - Financial Assets and Liabilities Subject to Fair Value Measurements (Details) link:presentationLink link:calculationLink link:definitionLink 9955537 - Disclosure - Fair Value Measurements - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955538 - Disclosure - Fair Value Measurements - Schedule of Fair Value of Contingent Consideration Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Marketable Securities and Equity Investments - Schedule of Cash Equivalents and Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955539 - Disclosure - Marketable Securities and Equity Investments - Schedule of Cash Equivalents and Marketable Securities (Details) link:presentationLink link:calculationLink link:definitionLink 9955540 - Disclosure - Marketable Securities and Equity Investments - Schedule of Available-for-Sale Debt Securities at Fair Value (Details) link:presentationLink link:calculationLink link:definitionLink 9955541 - Disclosure - Marketable Securities and Equity Investments - Available-for-Sale Debt Securities by Contractual Maturity (Details) link:presentationLink link:calculationLink link:definitionLink 9955542 - Disclosure - Marketable Securities and Equity Investments - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955543 - Disclosure - Marketable Securities and Equity Investments - Net Unrealized Gains (Losses) (Details) link:presentationLink link:calculationLink link:definitionLink 9955544 - Disclosure - Accumulated Other Comprehensive Income (Loss) (Details) link:presentationLink link:calculationLink link:definitionLink 9955545 - Disclosure - Hedging - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955546 - Disclosure - Hedging - Schedule of Notional Amount (Details) link:presentationLink link:calculationLink link:definitionLink 9955547 - Disclosure - Hedging - Schedule of Cash Flow Hedging Instruments (Details) link:presentationLink link:calculationLink link:definitionLink 9955548 - Disclosure - Hedging - Schedule of Derivative Fair Value (Details) link:presentationLink link:calculationLink link:definitionLink 9955549 - Disclosure - Hedging - Schedule of Offsetting Derivatives (Details) link:presentationLink link:calculationLink link:definitionLink 9955550 - Disclosure - Inventories (Details) link:presentationLink link:calculationLink link:definitionLink 9955551 - Disclosure - Property and Equipment - Schedule of Property and Equipment, Net (Details) link:presentationLink link:calculationLink link:definitionLink 9955552 - Disclosure - Property and Equipment - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Goodwill and Other Intangible Assets - Schedule of Intangible Assets and Goodwill (Details) link:presentationLink link:calculationLink link:definitionLink 9955553 - Disclosure - Goodwill and Other Intangible Assets - Schedule of Intangible Assets and Goodwill (Details) link:presentationLink link:calculationLink link:definitionLink 9955554 - Disclosure - Goodwill and Other Intangible Assets - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955555 - Disclosure - Goodwill and Other Intangible Assets - Schedule of Future Amortization Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955556 - Disclosure - Additional Balance Sheet & Cash Flow Information - Schedule of Cash, Cash Equivalents and Restricted Cash (Details) link:presentationLink link:calculationLink link:definitionLink 9955557 - Disclosure - Additional Balance Sheet & Cash Flow Information - Schedule of Prepaid Expenses and Other Current Assets (Details) link:presentationLink link:calculationLink link:definitionLink 9955558 - Disclosure - Additional Balance Sheet & Cash Flow Information - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955559 - Disclosure - Additional Balance Sheet & Cash Flow Information - Schedule of Accrued Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955560 - Disclosure - Additional Balance Sheet & Cash Flow Information - Schedule of Other Current Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955561 - Disclosure - Additional Balance Sheet & Cash Flow Information - Schedule of Other Long Term Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955562 - Disclosure - Leases - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955563 - Disclosure - Leases - Schedule of Components of Lease Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955564 - Disclosure - Leases - Schedule of Balance Sheet Classification of Lease Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955565 - Disclosure - Leases -Schedule of Maturities of Operating and Financing Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955565 - Disclosure - Leases -Schedule of Maturities of Operating and Financing Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955565 - Disclosure - Leases -Schedule of Maturities of Operating and Financing Lease Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955566 - Disclosure - Leases - Schedule of Weighted-Average Remaining Lease Terms and Discount Rates (Details) link:presentationLink link:calculationLink link:definitionLink 9955567 - Disclosure - Leases - Schedule of Supplemental Cash Flow Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955568 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Common Stock and Preferred Stock (Details) link:presentationLink link:calculationLink link:definitionLink 9955569 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Share Repurchase Program (Details) link:presentationLink link:calculationLink link:definitionLink 9955570 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Restricted Stock and Restricted Stock Units (Details) link:presentationLink link:calculationLink link:definitionLink 9955571 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Performance-based RSUs (PSUs) (Details) link:presentationLink link:calculationLink link:definitionLink 9955572 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Outstanding and Exercisable Options (Details) link:presentationLink link:calculationLink link:definitionLink 9955573 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Stock Options Outstanding and Exercisable (Details) link:presentationLink link:calculationLink link:definitionLink 9955574 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Employee Stock Purchase Plan (Details) link:presentationLink link:calculationLink link:definitionLink 9955575 - Disclosure - Common Stock, Preferred Stock and Equity Plans - Employee Benefits (Details) link:presentationLink link:calculationLink link:definitionLink 9955576 - Disclosure - Stock-based Compensation Expense - Schedule of Stock-based Compensation Expense by Line Item (Details) link:presentationLink link:calculationLink link:definitionLink 9955577 - Disclosure - Stock-based Compensation Expense - Schedule of Unrecognized Stock-Based Compensation Expense (Details) link:presentationLink link:calculationLink link:definitionLink 9955578 - Disclosure - Stock-based Compensation Expense - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955579 - Disclosure - Stock-based Compensation Expense - Schedule of weighted-average Assumptions (Details) link:presentationLink link:calculationLink link:definitionLink 9955580 - Disclosure - Income Taxes - Schedule of Components of Income and Provision for (Benefit from) Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955581 - Disclosure - Income Taxes - Schedule of Effective Income Tax Reconciliation (Details) link:presentationLink link:calculationLink link:definitionLink 9955582 - Disclosure - Income Taxes - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955583 - Disclosure - Income Taxes - Schedule of Deferred Tax Assets and Liabilities (Details) link:presentationLink link:calculationLink link:definitionLink 9955584 - Disclosure - Income Taxes - Net Operating Losses, Capital Losses, And Tax Credit Carryforwards (Details) link:presentationLink link:calculationLink link:definitionLink 9955585 - Disclosure - Income Taxes - Cash Paid for Income Taxes (Details) link:presentationLink link:calculationLink link:definitionLink 9955586 - Disclosure - Income Taxes - Unrecognized Tax Benefits (Details) link:presentationLink link:calculationLink link:definitionLink 9955587 - Disclosure - Commitments and Contingencies (Details) link:presentationLink link:calculationLink link:definitionLink 9955588 - Disclosure - Segment Information - Additional Information (Details) link:presentationLink link:calculationLink link:definitionLink 9955589 - Disclosure - Segment Information - Schedule of Revenues by Product (Details) link:presentationLink link:calculationLink link:definitionLink 9955590 - Disclosure - Segment Information - Schedule of Revenue by Geographic Location (Details) link:presentationLink link:calculationLink link:definitionLink 9955591 - Disclosure - Segment Information - Schedule of Significant Customers (Details) link:presentationLink link:calculationLink link:definitionLink 9955592 - Disclosure - Segment Information - Schedule of Significant Segment Expenses (Details) link:presentationLink link:calculationLink link:definitionLink 9955593 - Disclosure - Segment Information - Schedule of Property and Equipment, Net by Location (Details) link:presentationLink link:calculationLink link:definitionLink