Commitments and Contingencies - Legal Matters and Other Contingencies (Details) - USD ($) $ in Millions		3 Months Ended		9 Months Ended
	Oct. 10, 2025	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024	Dec. 31, 2024
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Product revenues		$ 3,076.4	$ 2,771.9	$ 8,811.3	$ 8,108.1
Loss contingencies		0.0		0.0		$ 0.0
Contingent liabilities		0.0		0.0		$ 0.0
ALYFTREK
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Product revenues		$ 247.0	$ 0.0	$ 457.7	$ 0.0
Royalty burden (as a percent)				4.00%
Subsequent Event | ALYFTREK
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Royalty burden (as a percent)	8.00%