Stock-based Compensation Expense and Share Repurchase Programs - Stock-based Compensation Expense (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2025	Sep. 30, 2024	Sep. 30, 2025	Sep. 30, 2024
Stock-based compensation expense:
Total stock-based compensation expense included in “Total costs and expenses”	$ 194.9	$ 184.6	$ 528.3	$ 530.7
Stock-based compensation expense related to inventories	(4.4)	(3.6)	(11.2)	(7.5)
Total stock-based compensation expense included in “Total costs and expenses”	194.9	184.6	528.3	530.7
Income tax effect	(47.5)	(64.6)	(159.2)	(224.3)
Total stock-based compensation expense, net of tax	147.4	120.0	369.1	306.4
Cost of sales
Stock-based compensation expense:
Total stock-based compensation expense included in “Total costs and expenses”	2.8	1.9	7.9	5.5
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation expense included in “Total costs and expenses”	116.0	111.0	315.7	327.5
Selling, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation expense included in “Total costs and expenses”	76.1	71.7	204.7	197.7
Restricted stock units (including PSUs)
Stock-based compensation expense:
Total stock-based compensation expense included in “Total costs and expenses”	190.8	184.8	517.1	522.7
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation expense included in “Total costs and expenses”	8.5	3.4	21.2	13.7
Stock options
Stock-based compensation expense:
Total stock-based compensation expense included in “Total costs and expenses”	$ 0.0	$ 0.0	$ 1.2	$ 1.8