Segment Information - Additional Information (Details) - USD ($)	3 Months Ended
	Mar. 31, 2025	Mar. 31, 2024
Disaggregation of Revenue [Line Items]
Product revenues	$ 2,770,200,000	$ 2,690,600,000
Depreciation and amortization expense	48,400,000	53,500,000
CASGEVY And JOURNAVX
Disaggregation of Revenue [Line Items]
Product revenues	$ 14,200,000	$ 0