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Stock-based Compensation Expense and Share Repurchase Programs (Tables)
 3 Months Ended
Mar. 31, 2025
Share-Based Payment Arrangement [Abstract]  
Schedule of Stock-based Compensation Expense by Line Item
During the three months ended March 31, 2025 and 2024, we recognized the following stock-based compensation expense:
Three Months Ended March 31,
20252024
(in millions)
Stock-based compensation expense by type of award:
Restricted stock units (including PSUs)$163.4 $187.2 
ESPP share issuances5.6 5.8 
Stock-based compensation expense related to inventories
(2.9)(1.1)
Total stock-based compensation expense included in “Total costs and expenses”
$166.1 $191.9 
Stock-based compensation expense by line item:
Cost of sales$2.6 $1.8 
Research and development expenses100.1 119.4 
Selling, general and administrative expenses63.4 70.7 
Total stock-based compensation expense included in “Total costs and expenses”
166.1 191.9 
Income tax effect(75.2)(79.0)
Total stock-based compensation expense, net of tax
$90.9 $112.9