Stock-based Compensation Expense and Share Repurchase Programs - Stock-based Compensation Expense (Details) - USD ($) $ in Millions	3 Months Ended
	Mar. 31, 2024	Mar. 31, 2023
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 191.9	$ 122.4
Stock-based compensation expense related to inventories	(1.1)	(0.4)
Total stock-based compensation expense included in “Total costs and expenses”	191.9	122.4
Income tax effect	(79.0)	(40.6)
Total stock-based compensation expense, net of tax	112.9	81.8
Cost of sales
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	1.8	1.9
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	119.4	76.3
Selling, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	70.7	44.2
Restricted stock units (including performance-based restricted stock units (“PSUs”))
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	187.2	115.9
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	5.8	5.5
Stock options
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 0.0	$ 1.4