Property and Equipment - Property and Equipment, Net (Details) - USD ($) $ in Millions	Dec. 31, 2022	Dec. 31, 2021
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	$ 2,135.7	$ 1,990.1
Less: accumulated depreciation	(1,027.3)	(896.0)
Total property and equipment, net	1,108.4	1,094.1
Buildings and improvements
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	903.1	892.5
Laboratory equipment, other equipment and furniture
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	476.5	407.3
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	410.9	363.5
Computers and software
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	312.1	293.7
Land
Property, Plant and Equipment [Line Items]
Total property and equipment, gross	$ 33.1	$ 33.1