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Nature of Business and Accounting Policies - Property and Equipment (Details)
12 Months Ended
Dec. 31, 2022
Buildings and improvements | Minimum  
Property, Plant and Equipment [Line Items]  
Property and equipment useful life 15 years
Buildings and improvements | Maximum  
Property, Plant and Equipment [Line Items]  
Property and equipment useful life 40 years
Laboratory equipment, other equipment and furniture | Minimum  
Property, Plant and Equipment [Line Items]  
Property and equipment useful life 7 years
Laboratory equipment, other equipment and furniture | Maximum  
Property, Plant and Equipment [Line Items]  
Property and equipment useful life 10 years
Computers and software | Minimum  
Property, Plant and Equipment [Line Items]  
Property and equipment useful life 3 years
Computers and software | Maximum  
Property, Plant and Equipment [Line Items]  
Property and equipment useful life 5 years