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Property and Equipment
12 Months Ended
Dec. 31, 2022
Property, Plant and Equipment [Abstract]  
Property and Equipment Property and Equipment
“Property and equipment, net” consisted of the following:
As of December 31,
20222021
(in millions)
Buildings and improvements$903.1 $892.5 
Laboratory equipment, other equipment and furniture476.5 407.3 
Leasehold improvements410.9 363.5 
Computers and software312.1 293.7 
Land33.1 33.1 
Total property and equipment, gross2,135.7 1,990.1 
Less: accumulated depreciation
(1,027.3)(896.0)
Total property and equipment, net
$1,108.4 $1,094.1 
We recorded depreciation expense of $148.3 million, $125.6 million and $109.5 million in 2022, 2021 and 2020, respectively, which includes our finance lease amortization.