Segment Information - Revenue by Geographic Location (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenues from External Customers and Long-Lived Assets [Line Items]
Total product revenues, net	$ 8,930.7	$ 7,574.4	$ 6,205.7
Product revenues, net
Revenues from External Customers and Long-Lived Assets [Line Items]
Total product revenues, net	8,930.7	7,573.4	6,202.8
United States | Product revenues, net
Revenues from External Customers and Long-Lived Assets [Line Items]
Total product revenues, net	5,699.3	5,287.3	4,826.4
Europe | Product revenues, net
Revenues from External Customers and Long-Lived Assets [Line Items]
Total product revenues, net	2,705.5	1,972.9	1,126.5
Other | Product revenues, net
Revenues from External Customers and Long-Lived Assets [Line Items]
Total product revenues, net	525.9	313.2	249.9
Total product revenues outside of the United States | Product revenues, net
Revenues from External Customers and Long-Lived Assets [Line Items]
Total product revenues, net	$ 3,231.4	$ 2,286.1	$ 1,376.4