<SEC-DOCUMENT>0000875320-22-000032-index.html : 20220805
<SEC-HEADER>0000875320-22-000032.hdr.sgml : 20220805
<ACCEPTANCE-DATETIME>20220805161132
ACCESSION NUMBER:		0000875320-22-000032
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		5
FILED AS OF DATE:		20220805
DATE AS OF CHANGE:		20220805
EFFECTIVENESS DATE:		20220805

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VERTEX PHARMACEUTICALS INC / MA
		CENTRAL INDEX KEY:			0000875320
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				043039129
		STATE OF INCORPORATION:			MA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-266582
		FILM NUMBER:		221140934

	BUSINESS ADDRESS:	
		STREET 1:		50 NORTHERN AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
		BUSINESS PHONE:		6173416393

	MAIL ADDRESS:	
		STREET 1:		50 NORTHERN AVENUE
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02210
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>a2022s-8x2013plan.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: a2022s-8x2013plan.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>a2022s-8_exhibit51xopinion.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: a2022s-8_exhibit51xopinion.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>a2022s-8_ex231xeyconsent.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: a2022s-8_ex231xeyconsent.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>4
<FILENAME>a2022s-8_ex107filingfeetab.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 4 - file: a2022s-8_ex107filingfeetab.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>ropesgrayheader.gif
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: ropesgrayheader.gif

</DOCUMENT>
</SEC-DOCUMENT>