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Stock-based Compensation Expense (Tables)
12 Months Ended
Dec. 31, 2020
Share-based Payment Arrangement [Abstract]  
Stock-Based Compensation Expense
The effect of stock-based compensation expense during the three years ended December 31, 2020 was as follows:
202020192018
(in thousands)
Stock-based compensation expense by line item:
Cost of sales
$5,579 $5,575 $4,543 
Research and development expenses262,690 224,558 203,112 
Sales, general and administrative expenses
161,192 130,356 117,392 
Total stock-based compensation expense included in costs and expenses
429,461 360,489 325,047 
Income tax effect
(146,959)(124,225)— 
Total stock-based compensation included in costs and expenses, net of tax$282,502 $236,264 $325,047 
Stock-Based Compensation Expense by Type of Award
The stock-based compensation expense by type of award during the three years ended December 31, 2020 was as follows:
202020192018
(in thousands)
Stock-based compensation expense by type of award:
Restricted stock units (including PSUs) and restricted stock$360,364 $254,276 $207,845 
Stock options59,722 96,737 107,854 
ESPP share issuances12,984 11,196 9,933 
Stock-based compensation expense related to inventories(3,609)(1,720)(585)
Total stock-based compensation expense included in costs and expenses
$429,461 $360,489 $325,047 
Unrecognized Stock-Based Compensation Expense
The following table sets forth the Company’s unrecognized stock-based compensation expense as of December 31, 2020, by type of award and the weighted-average period over which that expense is expected to be recognized:
As of December 31, 2020
Unrecognized Expense
Weighted-average Recognition Period
(in thousands)(in years)
Type of award:
Restricted stock units (including PSUs) and restricted stock$401,100 1.88
Stock options$62,392 1.77
ESPP share issuances$11,333 0.59
Schedule of Assumptions Used to Estimate the Grant Date Fair Value of Options
The fair value of each option granted during 2020, 2019 and 2018 was estimated on the date of grant using the Black-Scholes option pricing model with the following weighted-average assumptions:
202020192018
Stock options granted22,6361,520,7432,297,328
Expected stock price volatility35.87%36.99%40.50%
Risk-free interest rate0.43%2.32%2.61%
Expected term of options (in years)4.674.274.55
Expected annual dividends
Schedule of Assumptions Used to Estimate the Grant Date Fair Value Employee Stock Purchase Plan The following table reflects the weighted-average assumptions used in the Black-Scholes option pricing model for 2020, 2019 and 2018:
202020192018
Expected stock price volatility37.70%33.43%36.51%
Risk-free interest rate0.11%2.08%2.36%
Expected term (in years)0.710.740.75
Expected annual dividends