Stock-based Compensation Expense and Share Repurchase Programs - Stock-based Compensation Expense (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 115,706	$ 93,791
Stock-based compensation expense related to inventories	(1,194)	(452)
Share-based compensation expense by type of award	115,706	93,791
Income tax effect	(64,246)	(39,524)
Total stock-based compensation expense, net of tax	51,460	54,267
Cost of sales
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	1,361	1,338
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	72,687	59,715
Sales, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	41,658	32,738
Unvested restricted stock and restricted stock units (including PSUs)
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	97,149	63,510
Type of award:
Unrecognized Expense	$ 550,095
Weighted-average Recognition Period	2 years 3 months 7 days
Stock options
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 17,266	28,156
Type of award:
Unrecognized Expense	$ 109,086
Weighted-average Recognition Period	2 years 3 months 29 days
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation expense included in costs and expenses	$ 2,485	$ 2,577
Type of award:
Unrecognized Expense	$ 2,238
Weighted-average Recognition Period	12 days