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Revenue Recognition (Tables)
3 Months Ended
Mar. 31, 2020
Revenue from Contract with Customer [Abstract]  
Schedule of disaggregation of revenue
Product revenues, net consisted of the following:
 
Three Months Ended March 31,
 
2020
 
2019
 
(in thousands)
TRIKAFTA
$
895,233

 
$

SYMDEKO/SYMKEVI
173,159

 
320,275

ORKAMBI
234,138

 
293,007

KALYDECO
212,577

 
243,971

Total product revenues, net*
$
1,515,107

 
$
857,253


* The preceding table does not include collaborative and royalty revenues.
Total revenues from external customers and collaborators by geographic region consisted of the following:
 
Three Months Ended March 31,
 
2020
 
2019
 
(in thousands)
United States
$
1,187,588

 
$
641,104

Outside of the United States
 
 
 
Europe
257,391

 
167,751

Other
70,128

 
49,580

Total revenues outside of the United States
327,519

 
217,331

Total revenues
$
1,515,107

 
$
858,435