Stock-based Compensation Expense and Share Repurchase - (Details) - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2019	Mar. 31, 2018
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	$ 93,791	$ 78,136
Stock-based compensation expense related to inventories	(452)	(465)
Share-based compensation expense by type of award	93,791	78,136
Income tax effect	(39,524)	(21,859)
Total stock-based compensation included in costs and expenses, net of tax	54,267	56,277
Cost of sales
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	1,338	813
Research and development expenses
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	59,715	48,488
Sales, general and administrative expenses
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	32,738	28,835
Restricted stock and restricted stock units (including PSUs)
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	63,510	50,418
Type of award:
Unrecognized Expense	$ 475,787
Weighted-average Recognition Period	2 years 6 months 18 days
Stock options
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	$ 28,156	26,055
Type of award:
Unrecognized Expense	$ 193,321
Weighted-average Recognition Period	2 years 10 months 2 days
ESPP share issuances
Stock-based compensation expense:
Total stock-based compensation included in costs and expenses	$ 2,577	$ 2,128
Type of award:
Unrecognized Expense	$ 2,555
Weighted-average Recognition Period	5 months 5 days