Exhibit 10.47

Vertex Pharmaceuticals Annual Non-Employee Board Compensation
Annual Retainer		$100,000
Committee Chair Compensation
	Audit & Finance Committee Chair	$30,000 annual retainer
	Management Development & Compensation Committee Chair	$25,000 annual retainer
	Corporate Governance & Nominating Committee Chair	$20,000 annual retainer
	Science & Technology Committee Chair	$20,000 annual retainer
Committee Membership Fee (Non Chairs)
	Audit & Finance Committee Member	$15,000 annual retainer
	Management Development & Compensation Committee Member	$12,500 annual retainer
	Corporate Governance & Nominating Committee Member	$10,000 annual retainer
	Science & Technology Committee Member	$10,000 annual retainer
Lead Independent Director Compensation		$40,000 annual retainer
Annual Equity Grants
	On June 1 on each year of service, a $475,000 value-based award, comprised of restricted stock units ($275,000) and options ($200,000) •Options are fully vested upon grant •Restricted shares cliff vest on the 1 year anniversary of the grant date
Each of our non-employee directors is eligible to defer the cash and restricted stock portion of his/her compensation set forth above and elect to receive deferred stock units that convert to common stock in specified circumstances.