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Restructuring Liabilities (Tables)
 9 Months Ended
Sep. 30, 2017
Research and Development Restructuring  
Restructuring Cost and Reserve [Line Items]  
Activity related to restructuring liability
The restructuring charge and other activities recorded during the the three and nine months ended September 30, 2017 and the related liability balance as of September 30, 2017 were as follows:
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2017
 
2017
 
(in thousands)
Liability, beginning of the period
$
3,507

 
$
—

Restructuring (credits) expense
(125
)
 
12,315

Cash payments
(750
)
 
(7,869
)
Asset impairments and other non-cash items
—

 
(1,814
)
Liability, end of the period
$
2,632

 
$
2,632
Kendall Restructuring  
Restructuring Cost and Reserve [Line Items]  
Activity related to restructuring liability
The activities related to the restructuring liability for the three and nine months ended September 30, 2017 and 2016 were as follows:
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2017
 
2016
 
2017
 
2016
 
(in thousands)
Liability, beginning of the period
$
1,990

 
$
6,388

 
$
4,328

 
$
7,944

Restructuring expense
227

 
30

 
1,054

 
222

Cash payments
(4,003
)
 
(5,340
)
 
(12,962
)
 
(13,104
)
Cash received from subleases
2,732

 
2,866

 
8,526

 
8,882

Liability, end of the period
$
946

 
$
3,944

 
$
946

 
$
3,944
Fan Pier Move Restructuring  
Restructuring Cost and Reserve [Line Items]  
Activity related to restructuring liability
The activities related to the restructuring liability for the three and nine months ended September 30, 2017 and 2016 were as follows:
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2017
 
2016
 
2017
 
2016
 
(in thousands)
Liability, beginning of the period
$
1,521

 
$
4,863

 
$
3,626

 
$
5,964

Restructuring expense
235

 
90

 
490

 
472

Cash payments
(3,262
)
 
(4,199
)
 
(10,578
)
 
(10,451
)
Cash received from subleases
2,279

 
2,539

 
7,235

 
7,308

Liability, end of the period
$
773

 
$
3,293

 
$
773

 
$
3,293
Other Restructuring  
Restructuring Cost and Reserve [Line Items]  
Activity related to restructuring liability
The activities related to the Company’s other restructuring liabilities for the three and nine months ended September 30, 2016 were as follows:
 
Three Months Ended September 30,
 
Nine Months Ended September 30,
 
2016
 
2016
 
(in thousands)
Liability, beginning of the period
$
1,233

 
$
1,450

Restructuring expense
(112
)
 
344

Cash payments
(1,121
)
 
(1,794
)
Liability, end of the period
$
—

 
$
—