Intangible Assets and Goodwill (Details) - USD ($) $ in Thousands	Jun. 30, 2017	Dec. 31, 2016	Dec. 31, 2015	Jun. 04, 2015	Dec. 31, 2014	Oct. 31, 2014
Indefinite-Lived Intangible Assets [Line Items]
Intangible assets	$ 284,340	$ 284,340
Goodwill	50,384	50,384
Parion Sciences, Inc.
Indefinite-Lived Intangible Assets [Line Items]
Intangible assets				$ 255,300
BioAxone Biosciences Inc.
Indefinite-Lived Intangible Assets [Line Items]
In-process research and development intangible asset						$ 29,000
Variable Interest Entity, Primary Beneficiary
Indefinite-Lived Intangible Assets [Line Items]
In-process research and development intangible asset	284,300	284,300
Intangible assets	284,340	284,340
Goodwill	$ 19,391	$ 19,391
Variable Interest Entity, Primary Beneficiary | Parion Sciences, Inc.
Indefinite-Lived Intangible Assets [Line Items]
Intangible assets			$ 255,300
Variable Interest Entity, Primary Beneficiary | BioAxone Biosciences Inc.
Indefinite-Lived Intangible Assets [Line Items]
Intangible assets					$ 29,000