Stock-based Compensation Expense (Details) - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Stock-based compensation expense:
Stock-based compensation expense	$ 237,705,000	$ 231,025,000	$ 177,542,000
Less: stock-based compensation expense capitalized to inventories	(3,607,000)	(4,087,000)	(1,423,000)
Allocated stock-based compensation expense	237,705,000	$ 231,025,000	$ 177,542,000
Stock Options
Weighted-average assumptions for options and ESPP subscriptions granted
Expected annual dividends	$ 0
Employee stock purchase plan
Weighted-average assumptions for options and ESPP subscriptions granted
Weighted average fair value (usd per share)	$ 26.86	$ 37.84	$ 29.59
Expected stock price volatility (percent)	48.22%	47.20%	60.32%
Risk-free interest rate (percent)	0.56%	0.40%	0.09%
Expected term of options (in years)	9 months	8 months 20 days	9 months
Expected annual dividends	$ 0	$ 0	$ 0
Stock options
Stock-based compensation expense:
Stock-based compensation expense	114,768,000	$ 129,276,000	$ 99,961,000
Type of award:
Unrecognized Expense Net of Estimated Forfeitures	$ 157,819,000
Weighted-average Recognition Period (in years)	2 years 6 months
Weighted-average grant-date fair value, granted (in dollars per share)	$ 37.93	$ 52.16	$ 39.95
Weighted-average assumptions for options and ESPP subscriptions granted
Expected stock price volatility (percent)	46.77%	47.29%	50.86%
Risk-free interest rate (percent)	1.32%	1.61%	1.77%
Expected term of options (in years)	4 years 10 months 28 days	5 years 3 months 11 days	5 years 5 months 19 days
Expected annual dividends	$ 0	$ 0	$ 0
Employee Restricted Stock Option
Stock-based compensation expense:
Stock-based compensation expense	118,709,000	98,811,000	70,678,000
Type of award:
Unrecognized Expense Net of Estimated Forfeitures	$ 176,972,000
Weighted-average Recognition Period (in years)	2 years 4 months 21 days
Employee Stock Purchase Plan
Stock-based compensation expense:
Stock-based compensation expense	$ 7,835,000	7,025,000	8,326,000
Type of award:
Unrecognized Expense Net of Estimated Forfeitures	$ 4,080,000
Weighted-average Recognition Period (in years)	6 months 29 days
Research and development expenses
Stock-based compensation expense:
Stock-based compensation expense	$ 153,451,000	152,955,000	116,998,000
Sales, general and administrative expenses
Stock-based compensation expense:
Stock-based compensation expense	$ 84,254,000	$ 78,070,000	$ 60,544,000
Tranche one
Share-based Compensation Arrangement by Share-based Payment Award
Vesting rights percentage	33.33%
Tranche two
Share-based Compensation Arrangement by Share-based Payment Award
Vesting rights percentage	33.33%
Tranche three
Share-based Compensation Arrangement by Share-based Payment Award
Vesting rights percentage	33.33%
Minimum
Weighted-average assumptions for options and ESPP subscriptions granted
Performance Target	0.00%
Maximum
Weighted-average assumptions for options and ESPP subscriptions granted
Performance Target	200.00%
Financial performance shares | Performance Shares [Member]
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years
Non-financial performance shares | Performance Shares [Member]
Weighted-average assumptions for options and ESPP subscriptions granted
Vesting period	3 years